PMID: 2123730Sep 17, 1990Paper

Environmental stress increases extracellular dopamine in striatum of 6-hydroxydopamine-treated rats: in vivo microdialysis studies

Brain Research
K A KeefeE D Abercrombie

Abstract

Bilateral intraventricular injections of 6-hydroxydopamine depleted dopamine (DA) in striatal tissue of rats by 88%. Tail shock increased DA in striatal extracellular fluid of these rats from 10 to 17 pg/20 microliters as measured by microdialysis, values less than half those seen in normal striatum. The increase was observed even in rats that were akinetic. DA in extracellular fluid after stress was negatively correlated with behavioral performance. Thus, residual nigrostriatal DA neurons are responsive to stress but do not produce normal DA levels in striatal extracellular fluid.

References

Jun 1, 1979·Journal of Comparative and Physiological Psychology·E M StrickerM J Zigmond
Sep 16, 1976·Nature·A M ThierryJ Glowinski
Jan 1, 1988·Annals of the New York Academy of Sciences·A J Dunn
Nov 1, 1985·Annals of Neurology·A M SnyderM J Zigmond

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Citations

Jan 1, 1993·Journal of Neural Transmission. General Section·A A Grace
Jan 1, 1993·Journal of Neural Transmission. General Section·K A KeefeE D Abercrombie
Apr 1, 1994·Pharmacology, Biochemistry, and Behavior·D ShurtleffR Harford
Aug 1, 1995·Pharmacology, Biochemistry, and Behavior·R E TesselC J Stodgell
Dec 1, 1995·Pharmacology, Biochemistry, and Behavior·A A Hegarty, W H Vogel
Jan 1, 1996·Pharmacology, Biochemistry, and Behavior·P KehoeW J Shoemaker
Oct 1, 1995·Behavioural Brain Research·B H Westerink
Apr 9, 2005·Experimental Neurology·Nadine P Poulton, Gillian D Muir
Jan 16, 2003·Physiology & Behavior·Amanda D SmithMichael J Zigmond
Feb 1, 1997·Pharmacology, Biochemistry, and Behavior·A Saldívar-GonzálezR Mondragón-Ceballos
Jul 2, 2003·Psychiatry Research·Fotis FotiouGeorge Kaprinis
Apr 5, 2003·Journal of Neurochemistry·Ann D CohenMichael J Zigmond
Apr 17, 2008·The European Journal of Neuroscience·Lori K SmithGerlinde A Metz
Feb 8, 2005·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Leo SherJ John Mann
Oct 18, 2011·Experimental Neurology·Ann M HemmerleKim B Seroogy
Nov 21, 2007·Reviews in the Neurosciences·Gerlinde A Metz
Feb 12, 2017·Physiology & Behavior·Udaiyappan JanakiramanGilles J Guillemin
Feb 16, 2000·Molecular Psychiatry·L PaniG L Gessa
Jan 25, 2002·Annals of the New York Academy of Sciences·G M Cragg, D J Newman
Nov 3, 2007·Pediatrics·Wolff SchlotzDavid I W Phillips

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