PMID: 7539998Mar 1, 1995Paper

Environmental transmission of hepatitis B and hepatitis C viruses within the hemodialysis unit

Artificial Organs
M Cendoroglo NetoS A Draibe

Abstract

The hepatitis B virus (HBV) can be transmitted in the dialysis setting through blood transfusions and environmental surfaces. Transfusion related hepatitis C virus (HCV) infection is very well known, but only recently the environmental transmission of this virus was postulated. In order to study the prevalence, mechanisms of transmission, and the ALT patterns of HBV and HCV infections in hemodialysis and CAPD patients before the implementation of HBV vaccination and HCV screening in the blood bank, we conducted a study from January 1987 to January 1990. Sera from 185 hemodialysis and 124 CAPD patients were stored in this period and later analyzed for HBsAg, anti-HBc, anti-HBs, and anti-HCV (second generation ELISA). The prevalence of any HBV marker was 55.7% (103/185) for hemodialysis patients and 31.5% (39/124) for CAPD patients (hemodialysis vs. CAPD, p < 0.001). The prevalence of positive anti-HCV was 35.1% (65/185) for hemodialysis and 33.9% (42/124) for CAPD patients (not significant). There was a significant association between HBV markers positivity and anti-HCV positivity. The multivariate analysis of risk factors revealed an association of the positivity of each virus with the duration of renal replacement therapy (RRT...Continue Reading

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Citations

Sep 5, 2002·Journal of Medical Virology·Sheila A TelesClara F T Yoshida
Aug 1, 1996·Journal of Perianesthesia Nursing : Official Journal of the American Society of PeriAnesthesia Nurses·M Csete
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Jan 5, 2000·Artificial Organs·S A TelesC F Yoshida
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