Enzymatic Oxydate-Triggered Self-Illuminated Photoelectrochemical Sensing Platform for Portable Immunoassay Using Digital Multimeter

Analytical Chemistry
Jian ShuDianping Tang

Abstract

Herein a novel split-type photoelectrochemical (PEC) immunosensing platform was designed for sensitive detection of low-abundance biomarkers (prostate-specific antigen, PSA, used in this case) by coupling a peroxyoxalate chemiluminescence (PO-CL) self-illuminated system with digital multimeter (DMM) readout. The PEC detection device consisted of a capacitor/DMM-joined electronic circuit and a PO-CL-based self-illuminated cell. Initially, reduced graphene oxide-doped BiVO4 (BiVO4-rGO) photovoltaic materials with good photoelectric properties was integrated into the capacitor/DMM-joined circuit for photocurrent generation in the presence of hydrogen peroxide (H2O2, as the hole-trapping reagent). A sandwich-type immunoreaction with target PSA was carried out in capture antibody-coated microplates by using glucose oxidase/detection antibody-conjugating gold nanoparticle (pAb2-AuNP-GOx). Accompanying the sandwiched immunocomplex, the labeled GOx could oxidize glucose to produce H2O2. The as-generated H2O2 could act as the coreaction reagent to trigger the chemiluminescence of the peroxyoxalate system and the PEC reaction of the BiVO4-rGO. Meanwhile, the self-illuminated light could induce photovoltaic material (BiVO4-rGO) to produce...Continue Reading

References

Sep 15, 2005·Chemical Reviews·Waldemar AdamValeri P Kazakov
Jul 27, 2006·Journal of the American Chemical Society·Naoufel HaddourSerge Cosnier
Mar 4, 2008·Journal of the American Chemical Society·Anusorn KongkanandPrashant V Kamat
Feb 21, 2005·Physical Chemistry Chemical Physics : PCCP·Jóhannes Reynisson, Steen Steenken
Jan 21, 2011·Analytical Chemistry·Jacqui L DelaneyWei Shen
May 25, 2012·Chemical Communications : Chem Comm·Wenwen TuHuangxian Ju
Feb 22, 2013·ACS Applied Materials & Interfaces·Ronit FreemanItamar Willner
Mar 13, 2013·Journal of the American Chemical Society·Hashem Akhavan-TaftiWenhua Xie
Apr 16, 2014·Biosensors & Bioelectronics·Yong Duk HanHyun C Yoon
Jun 17, 2014·Chemical Reviews·Wei-Wei ZhaoHong-Yuan Chen
Aug 26, 2014·ACS Applied Materials & Interfaces·Xianxiang ZengZhihui Dai
Sep 17, 2014·Chemical Society Reviews·Wei-Wei ZhaoHong-Yuan Chen
Oct 12, 2014·Analytical and Bioanalytical Chemistry·Dennis B PacardoFrances S Ligler
Nov 28, 2014·Luminescence : the Journal of Biological and Chemical Luminescence·Abdolraouf Samadi-Maybodi, Reza Akhoondi
Mar 22, 2015·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Pourya BiparvaSayed Yahya Kazemi
May 30, 2015·Analytical Chemistry·Wei-Wei ZhaoHong-Yuan Chen

❮ Previous
Next ❯

Citations

Apr 25, 2018·Chemistry : a European Journal·Yang ZangHuan Pang
Sep 29, 2019·Chemistry : a European Journal·Laura DelafresnayeChristopher Barner-Kowollik
Mar 13, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Zhenli Qiu, Dianping Tang
Sep 8, 2017·Chemistry, an Asian Journal·Jian Shu, Dianping Tang
Jul 14, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Kaili NiuYanyan Song
Oct 2, 2019·Frontiers in Chemistry·Amanda VictoriousLeyla Soleymani
Dec 28, 2018·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yue ZhangYanfei Shen
Apr 29, 2021·Chemical Communications : Chem Comm·Fabian R BloesserChristopher Barner-Kowollik
Dec 30, 2017·Analytical Chemistry·Yanmei Xin, Zhonghai Zhang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.