Enzymatic release of oligosaccharides from glycoproteins for chromatographic and electrophoretic analysis

Journal of Chromatography. a
R A O'Neill

Abstract

For most separations-based analyses of glycoprotein oligosaccharides, the first step is release of the oligosaccharides from the polypeptide. Historically, O-linked and N-linked oligosaccharides have been released from glycoproteins using chemical means, such as alkaline degradation (beta-elimination) or hydrazinolysis. In the last two decades, a growing repertoire of enzymes, including endoglycosidases and glycoamidases, able to release glycoprotein oligosaccharides under mild conditions, have become available. This review traces the discovery, characterization and use of these glycoprotein oligosaccharide releasing enzymes. Emphasis is placed on providing information of practical value for the researcher wishing to incorporate enzymatic oligosaccharide release into their study of glycoprotein oligosaccharide structure and function.

References

Jun 7, 1976·Biochemical and Biophysical Research Communications·V P BhavanandanE A Davidson
Jan 1, 1978·Methods in Enzymology·T Muramatsu
Jun 20, 1977·Biochemical and Biophysical Research Communications·N Takahashi
May 23, 1976·Biochemical and Biophysical Research Communications·S ChienY Li
Aug 15, 1986·Carbohydrate Research·B Bendiak, D A Cumming
Jan 1, 1989·Annual Review of Biochemistry·G W HartW G Kelly
Aug 1, 1989·European Journal of Immunology·F AubritA Bernard
Jan 1, 1987·Methods in Enzymology·R D McCoy, F A Troy
Mar 1, 1986·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·H Schachter
May 1, 1987·Analytical Biochemistry·S HiraniJ R Rasmussen
Jan 1, 1985·Annual Review of Biochemistry·R Kornfeld, S Kornfeld
Aug 13, 1985·Biochemistry·A L TarentinoT H Plummer
Jan 1, 1971·Archives of Biochemistry and Biophysics·R N Iyer, D M Carlson
Jun 29, 1966·Biochimica Et Biophysica Acta·Z YosizawaK Schmid
Jul 1, 1984·Archives of Biochemistry and Biophysics·H H Freeze, J R Etchison
Apr 1, 1984·Journal of Biochemistry·T MizuochiA Kobata
Mar 1, 1982·Archives of Biochemistry and Biophysics·Y TachibanaA Kobata
Aug 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·J H Elder, S Alexander
Apr 15, 1983·Biochemical and Biophysical Research Communications·K SugiyamaN Takahashi
Jan 1, 1994·Methods in Enzymology·A K Menon

❮ Previous
Next ❯

Citations

Sep 18, 1998·Electrophoresis·N H Packer, M J Harrison
Nov 6, 2009·Glycoconjugate Journal·Elizabeth Higgins
Sep 5, 2012·Glycoconjugate Journal·Milos V NovotnyBenjamin F Mann
Aug 1, 1997·Current Opinion in Biotechnology·P M Rudd, R A Dwek
Feb 14, 2002·Chemical Reviews·Yehia Mechref, Milos V Novotny
Mar 28, 2013·Chemical Reviews·William R AlleyMilos V Novotny
Dec 14, 1999·Protein Science : a Publication of the Protein Society·V RaoP Van Roey
Dec 23, 2015·International Journal of Molecular Sciences·Manveen K Sethi, Susan Fanayan
Apr 30, 2003·Journal of Mass Spectrometry : JMS·Lobvi E Matamoros FernándezPeter Roepstorff
Jan 12, 2007·Seminars in Cell & Developmental Biology·David M Cohen
Dec 1, 2006·Biochimica Et Biophysica Acta·Hildegard Geyer, Rudolf Geyer
Sep 25, 2015·Analytical Chemistry·Roberto VinciguerraLeila Birolo
Oct 7, 2014·Biochimica Et Biophysica Acta·Steven B LeverySergey Y Vakhrushev
Mar 31, 2015·Chromatographia·Archana ShubhakarManfred Wuhrer
May 28, 2014·Glycobiology·Catharina SteentoftHenrik Clausen
Feb 6, 2018·Expert Review of Proteomics·Kelly M FultonSusan M Twine
May 18, 2020·Biochimica Et Biophysica Acta. General Subjects·Zhijue XuYan Zhang
Oct 31, 2009·Analytical Chemistry·John A GoetzYehia Mechref
Apr 9, 2013·Analytical Chemistry·Stefan MittermayrAndrás Guttman
Aug 17, 2021·Frontiers in Neuroanatomy·Md Mahmudul HasanMitsutoshi Setou
Dec 30, 2006·Analytical Chemistry·Caterina TemporiniGabriella Massolini
Oct 1, 2021·ACS Chemical Biology·Landon J Edgar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.