Enzymatic variability of Candida krusei isolates in a course of fungal infection in a liver transplant recipient

Transplantation Proceedings
D KaweckiM Luczak

Abstract

Transplant recipients are at high risk of fungal infections. The main site of fungal infections in patients undergoing liver transplantation is the abdominal cavity. One factor determining the pathogenicity of fungi is their ability to secrete hydrolytic enzymes. The aim of this study was to assess the enzymatic activity of Candida krusei, which caused an infection in a liver transplant recipient. The clinical specimens included swabs of throat, nose, and two drains, as well as bile, stool, and abdominal cavity aspirate. The yeast-like fungi isolated were identified by an ID 32 C test (bioMérieux) and their enzymatic activity assayed with the use of an API-ZYM test. Two biotypes of C. krusei were identified, depending on the source of the clinical specimen. The C. krusei isolates cultured from a throat swab, a nasal swab, and one of the drains secreted esterase lipase C8 (enzyme IV) and valine arylamidase (enzyme VII), in contrast to those isolated from the bile, abdominal cavity fluid, another drain, and stool. Characterization of two biotypes of C. krusei isolates cultured from different clinical samples from several infection sites indicated an ability of C. krusei to adapt to variable environmental conditions.

References

May 1, 1995·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J BriegelG Ruckdeschel
Jan 11, 2000·Clinical Microbiology Reviews·M A Ghannoum
Jun 6, 2000·The Journal of Antimicrobial Chemotherapy·N Singh
Apr 20, 2001·The European Respiratory Journal·L P NicodN Howarth
Jul 4, 2001·Trends in Microbiology·R A Calderone, W A Fonzi
Aug 31, 2002·Chembiochem : a European Journal of Chemical Biology·Jean-Louis Reymond, Denis Wahler
Nov 30, 2002·International Journal of Antimicrobial Agents·M M WroblewskaM Luczak
Oct 9, 2003·Journal of Medical Microbiology·Annemarie Borst, Ad C Fluit
Jul 9, 2004·Current Opinion in Infectious Diseases·Robin K Avery

❮ Previous
Next ❯

Citations

Jul 25, 2012·Canadian Journal of Microbiology·Jay Shankar Singh YadavR Y Surampalli
May 14, 2020·Medical Mycology·A T JamiuC H Pohl

❮ Previous
Next ❯

Related Concepts

Related Feeds

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Bacteriotherapy

Bacteriotherapy, also known as fecal transplantation, involves the transfer of stool from a healthy donor into the gastrointestinal tract for the purpose of treating recurrent C. difficile colitis. Here is the latest on bacteriotherapy.

Bacteriotherapy (ASM)

Bacteriotherapy, also known as fecal transplantation, involves the transfer of stool from a healthy donor into the gastrointestinal tract for the purpose of treating recurrent C. difficile colitis. Here is the latest on bacteriotherapy.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Related Papers

Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
James Y FindlayDavid J Plevak
Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
Elisabetta CeruttiMauro Salizzoni
Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
Janis E Blair, S Kusne
© 2021 Meta ULC. All rights reserved