PMID: 3751500Jun 1, 1986Paper

Enzyme-linked immunosorbent assay for detection of antibodies to extractable muscle antigens in myasthenia gravis

Acta Neurologica Scandinavica
V S VianaW Cossermelli

Abstract

A purified citric acid soluble extract from human skeletal muscle (AEMA) and a phosphate-buffered saline extract from rabbit muscle acetone powder (EMA) were used to coat polystyrene beads in an enzyme-linked immunosorbent assay (ELISA). From 54 patients with myasthenia gravis, positive results were observed in 14. Five of 6 patients with thymoma had high levels of antibodies. With the diagnostic difficulties in detecting small and medium-sized thymoma, a sensitive assay for detection of antibodies to muscle antigen may be an important supplementary tool to detect tumors at early stages.

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Citations

Nov 1, 1989·Acta Neurologica Scandinavica·P E MarchioriR M de Oliveira
May 21, 1999·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·C SchouN E Fiehn
May 20, 1998·Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B·L F Calvinho, S P Oliver
Jun 30, 2010·Reviews in Medical Virology·Kevin E Brown
Nov 3, 2010·BJOG : an International Journal of Obstetrics and Gynaecology·R F LamontR Romero
Jan 1, 1990·Revista Do Instituto De Medicina Tropical De São Paulo·J P NascimentoB J Cohen
Dec 1, 1994·Epidemiology and Infection·Y MatsunagaN Muroi
Jul 1, 1989·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·S J Naides
Dec 9, 2015·Journal of Clinical Pathology·Jonathan R Kerr
Jun 21, 2018·Frontiers in Cellular and Infection Microbiology·Safder S Ganaie, Jianming Qiu

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