PMID: 6413822Jan 1, 1983Paper

Enzyme patterns in D. melanogaster imaginal discs: distribution of glucose-6-phosphate and 6-phosphogluconate dehydrogenase

Molecular & General Genetics : MGG
G N CunninghamD T Kuhn

Abstract

Distribution of glucose-6-phosphate dehydrogenase (G6PD) and 6-phospho-gluconate dehydrogenase (6PGD) in imaginal discs of Drosophila melanogaster was determined. Differential patterns of staining were found in all discs examined, i.e., eye-antennal, wing, leg, labial and genital. By using null mutants for either G6PD or 6PGD, the enzymes were shown to have the same distribution patterns. Staining with glucose-6-phosphate as a substrate resulted in the detection of both G6PD and 6PGD. Results of staining discs from homoeotic mutants indicate that the enzyme distribution patterns are under genetic control. In the presence of the homoeotic engrailed (en) mutation which transforms posterior wing compartment into anterior, the G6PD pattern of the posterior compartment of the wing disc was specifically transformed toward that of the anterior compartment. The bithorax series of homoeotic mutants was similarly investigated. The bithorax (bx3) mutation transforms the anterior part of the haltere to anterior wing blade. Similarly the G6PD pattern in the anterior haltere disc transforms to that of anterior wing disc. The complimentary transformation, postbithorax (pbx) results in a change of the posterior part of the haltere to posterior...Continue Reading

References

Aug 1, 1977·Journal of Morphology·I I Deak
Jan 7, 1977·Molecular & General Genetics : MGG·D T Kuhn, G N Cunningham
Aug 1, 1976·Developmental Biology·D T Khun, G N Cunningham
Oct 15, 1976·Developmental Biology·D F ReadyS Benzer
Jan 1, 1976·Annual Review of Genetics·R J MacIntyre, S J O'Brien
Oct 24, 1973·Nature: New Biology·A Garcia-BellidoG Morata
Jun 1, 1970·Biochemical Genetics·D A Wright, C R Shaw
Mar 1, 1968·Experimental Gerontology·J Delcour, M J Heuts
May 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·M P Weir, C W Lo
Jun 1, 1973·Wilhelm Roux' Archiv Für Entwicklungsmechanik Der Organismen·Willem J Ouweneel, Jitse M van der Meer
Jun 1, 1978·Wilhelm Roux's Archives of Developmental Biology·J A Campos-Ortega, Michael Waitz
Mar 1, 1977·Wilhelm Roux's Archives of Developmental Biology·Th E Sprey

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Citations

Feb 1, 1983·Developmental Biology·D T KuhnT E Sprey
Jun 1, 1990·Roux's Archives of Developmental Biology : the Official Organ of the EDBO·Lois A Abbott, Th E Sprey

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