Eosinophil granule cationic proteins: eosinophil activation markers

La Revue de médecine interne
P GuilpainL Mouthon

Abstract

Eosinophils play a central role in the pathogenesis of allergic diseases and host protection against parasites, especially against helminths. Eosinophil granules contain cytotoxic proteins, including cationic proteins: major basic protein (MBP), eosinophil cationic protein (ECP), eosinophil peroxidase (EPO) and eosinophil derived neurotoxin (EDN). Eosinophil granule proteins are implicated in the occurrence of allergic diseases and Churg-Strauss syndrome. These proteins are activation markers of eosinophils and may be useful in clinical practice.

References

Aug 1, 1995·The Journal of Allergy and Clinical Immunology·V CottinJ F Cordier
Jul 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·B ZimmermanS Ahlstedt
May 1, 1997·American Journal of Respiratory and Critical Care Medicine·M M PizzichiniF E Hargreave
Jan 14, 2003·American Journal of Respiratory and Critical Care Medicine·Emiko NoguchiMasanao Shibasaki

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Citations

Oct 28, 2015·Autoimmunity Reviews·Benjamin ChaigneLuc Mouthon
Mar 14, 2016·La Revue de médecine interne·B ChaigneB Terrier
Nov 26, 2009·Acta Ophthalmologica·Osmo KariPetri T Kovanen

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