PMID: 3988417Mar 1, 1985Paper

Eosinophilic cellulitis (Wells' syndrome)

International Journal of Dermatology
G B FisherP H Cooper


Two patients with eosinophilic cellulitis are reported and 22 additional cases from the literature are reviewed. Cutaneous lesions are variable in appearance and may be confused with cellulitis, urticaria, insect bites, or contact dermatitis. Microscopically, there is a dense dermal infiltrate of eosinophils. Subsequently, granulomatous features with characteristic "flame figures" become apparent. Peripheral eosinophilia is common. The etiology of eosinophilic cellulitis is unknown, although a hypersensitivity mechanism is suspected. Treatment with systemic corticosteroids is frequently effective, but the disease is often characterized by relapses that can occur for several years.


Jan 1, 1979·The British Journal of Dermatology·G C Wells, N P Smith
May 1, 1979·Archives of Dermatology·G T Spigel, R K Winkelmann
Feb 1, 1983·The Journal of Pediatrics·F T SaulsburyJ M Kennaugh
Jun 1, 1982·Dermatologica·C VarottiA Patrizi
Jul 1, 1981·Archives of Dermatology·T NielsenH Søgaard
Apr 1, 1980·The Australasian Journal of Dermatology·R Marks


Sep 10, 1998·International Journal of Dermatology·I S FriedmanA N Sapadin
Mar 1, 2002·The Australasian Journal of Dermatology·Li-Chuen WongMaureen Rogers
Sep 1, 1988·Clinical and Experimental Dermatology·J A Newton, M W Greaves
Jun 19, 1998·Journal of the American Academy of Dermatology·M D DavisK M Leiferman
Aug 22, 2000·The British Journal of Dermatology·D CanonneE Delaporte
Nov 28, 2001·Clinical and Experimental Dermatology·S A Holme, P McHenry
Feb 24, 2001·Pediatric Dermatology·R T KuwaharaM G Eisner
Jun 10, 2004·Journal of Cutaneous Pathology·Jane M Lynch, Terry L Barrett
Feb 1, 1991·The British Journal of Dermatology·M ReichelR Gandour-Edwards
Jul 1, 1997·Pediatric Dermatology·B Z GartyY L Danon
Feb 12, 1998·The British Journal of Dermatology·E DiridlA Tanew
Jul 1, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·F RäßlerP Elsner
Feb 13, 2003·International Journal of Dermatology·Meena Moossavi, Darius R Mehregan
Apr 1, 1997·International Journal of Dermatology·D K ChangK Jimbow
Jul 1, 1995·The British Journal of Dermatology·H M HornM J Tidman

Related Concepts

Related Feeds


Cellulitis (erysipelas) is a recurring and debilitating bacterial infection of the skin and underlying tissue. Discover the latest research on cellulitis here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

International Journal of Dermatology
D P Clark, P C Anderson
Clinical and Experimental Dermatology
H M van den Hoogenband
Journal of the American Academy of Dermatology
C R AndersonJ S Prendiville
© 2021 Meta ULC. All rights reserved