PMID: 6972219May 1, 1981Paper

Eosinophilic fasciitis: clinical, laboratory, and microscopic considerations

Arthritis and Rheumatism
L T KentR W Moskowitz

Abstract

Two patients with clinical and pathologic features of eosinophilic fasciitis manifested serologic and systemic abnormalities that raised the question of the fundamental nature and relationship of eosinophilic fasciitis to scleroderma. In addition to the characteristic features of eosinophilic fasciitis, both patients exhibited arthritis, a predominantly mononuclear cell infiltration of muscles with normal serum muscle enzyme levels, weakly positive serum antinuclear factor, IgA deficiency, and abnormalities of pulmonary function. In addition, one patient had wide-mouthed colonic diverticulae and synovial deposits consistent with amyloid; the second patient had bone marrow hypoplasia. Although corticosteroid therapy was of benefit, hydroxychloroquine and potassium para-aminobenzoate were of further help in controlling the disorder. Biopsies from the two patients revealed inflammatory lesions to be heaviest deep in the skeletal muscle; fascia was only minimally inflamed with mild fibrosis. The findings suggest that striking fibroinflammatory lesions noted in the fascia in some patients with eosinophilic fasciitis may derive largely from spillover of lesions in neighboring skeletal muscle.

References

Oct 1, 1979·The Journal of Dermatologic Surgery and Oncology·J K Robinson
Sep 1, 1979·Journal of the American Academy of Dermatology·M JarrattW Ramsdell
Jan 1, 1978·Arthritis and Rheumatism·P J ClementsH E Paulus
Aug 1, 1977·Annals of the Rheumatic Diseases·R M BennettL Keogh
Nov 1, 1975·Arthritis and Rheumatism·G P Rodnan
Jan 1, 1976·Annals of Internal Medicine·H R Schumacher
Dec 12, 1968·The New England Journal of Medicine·T B Tomasi
Aug 1, 1968·Arthritis and Rheumatism·T A MedsgerJ W Vester
Apr 1, 1980·Annals of Internal Medicine·J Rosenthal, M D Benson
Feb 1, 1980·Seminars in Arthritis and Rheumatism·T L Moore, J Zuckner

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Citations

Sep 1, 1984·Clinical Rheumatology·M M Steven, A Cats
Dec 1, 1991·Clinical Rheumatology·A E LoeligerJ W Bijlsma
Mar 1, 1993·Clinical Rheumatology·A L WongK K Colburn
May 3, 2000·The British Journal of Dermatology·R SchienerM Kerscher
Apr 9, 2010·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Konstantinos Loupasakis, Chris T Derk
May 1, 1992·Journal of Internal Medicine·D W Ching, M R Leibowitz
Mar 1, 1986·Journal of Neurology, Neurosurgery, and Psychiatry·H R JonesS W Margles
Dec 24, 2004·AJR. American Journal of Roentgenology·Franz BaumannDominik Weishaupt
Sep 1, 1984·Clinical Rheumatology·J M De Jonge-BokA Cats
Sep 22, 2001·The American Journal of Medicine·K H CostenbaderR J Anderson
Jul 1, 1984·Clinical and Experimental Dermatology·A D OrmerodN Edward
Aug 1, 1985·Journal of the American Academy of Dermatology·W W PietteE Foucar
Oct 20, 2018·Internal Medicine·Shohei AsadaHitoshi Yoshiji
Jan 1, 1984·Scandinavian Journal of Rheumatology·S CintiC Cervini
Apr 3, 2001·Journal of Cutaneous Medicine and Surgery·S R FlorellM J Petersen
Nov 2, 1982·Klinische Wochenschrift·P HerzerM Schattenkirchner
Feb 1, 1992·Seminars in Arthritis and Rheumatism·J E NaschitzJ H Boss
Sep 1, 1982·Muscle & Nerve·D B SimonR L Sufit

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