PMID: 8599447Oct 1, 1995Paper

Eosinophilic folliculitis. The histologic spectrum

The American Journal of Dermatopathology
T H McCalmontT G Berger

Abstract

We sought to define the light microscopic features of eosinophilic folliculitis as it occurs in human immunodeficiency virus (HIV)-infected individuals. The histologic findings of 52 biopsies from 50 patients were graded and compared with six biopsies of suppurative folliculitis from HIV-infected individuals. In all patients, clinical examination showed an eruption of pruritic follicular papules, and the folliculocentric nature of the disorder was confirmed histologically. Perifollicular infiltrates of lymphocytes and eosinophils were identified in all study biopsies, and there was also spongiosis of follicular epithelium. The inflammatory reaction was focused at the level of the follicular isthmus and the sebaceous duct. In all biopsies, lymphocytes and/or eosinophils were present within spongiotic follicular epithelium, but intrafollicular neutrophils were rare. Sebaceous glandular inflammation, eosinophilic pustule formation, and follicular rupture were present in less than half of the biopsies. Small numbers of microbes (bacteria, yeast, Demodex) were identified in 25% of the study biopsies in routine or special stains, but the organisms were away from areas of inflammation and were interpreted as nonpathogenic flora. The b...Continue Reading

Citations

Oct 12, 2000·Clinics in Dermatology·G E Rodwell, T G Berger
Dec 21, 2000·International Journal of Dermatology·J B RosatelliA M Roselino
Nov 13, 2001·International Journal of Dermatology·P PatroneA Frattasio
Jul 9, 2002·International Journal of Dermatology·Camilla VassalloGiovanni Borroni
May 22, 2001·AIDS Patient Care and STDs·M A Fung, J A Reed
Jun 24, 1999·The American Journal of Dermatopathology·P K RamdialJ Aboobaker
Jan 5, 2000·Sexually Transmitted Infections·S Simpson-DentR C Staughton
Mar 12, 2003·American Journal of Clinical Dermatology·Fiza Singh, Donald Rudikoff
Jun 1, 2006·American Journal of Clinical Dermatology·Sareeta R S ParkerCalvin O McCall
Sep 6, 2013·Journal of the International AIDS Society·Terry T FarsaniToby A Maurer
Jul 5, 2001·Pediatric Dermatology·G MarchiniS Lonne-Rahm
Mar 28, 2012·Seminars in Hematology·Rojelio Mejia, Thomas B Nutman
Jul 20, 1999·Dermatologic Clinics·C Jaworsky, A C Gilliam
Nov 18, 2003·The Australasian Journal of Dermatology·Steven Kossard
Jul 7, 2007·International Journal of Dermatology·Judith M Budavari, Wayne Grayson
Feb 27, 2019·American Journal of Clinical Dermatology·Khatiya ChelidzeEsther Ellen Freeman
May 20, 2003·Journal of Cutaneous Pathology·J Yu-Yun LeeHamm-Ming Sheu
Jul 19, 2003·The Australasian Journal of Dermatology·Kimble M OpieJames B Rohr
Apr 25, 2000·The Journal of Dermatology·N Rattana-Apiromyakij, P Kullavanijaya
Dec 1, 1996·Seminars in Cutaneous Medicine and Surgery·J Machado-PintoL E Golitz
Jan 26, 2011·Journal of the International AIDS Society·Filiberto Cedeno-LaurentJose R Trujillo
Oct 10, 2007·Archives of Pathology & Laboratory Medicine·Wajiha SufyanYoke-Sun Lee
Sep 18, 2007·Immunology and Allergy Clinics of North America·Thomas B Nutman

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