PMID: 6975871Nov 1, 1981Paper

Eosinophilic granuloma of lung. Clinical aspects of primary histiocytosis in the adult

Medicine
P J FriedmanJ Sokoloff

Abstract

One hundred cases of eosinophilic granuloma diagnosed by open lung biopsy were reviewed. There were 60 women and 40 men, ages 18 to over 60 years. Radiographs and clinical histories were contributed by physicians referring the cases for pathological consultation. Clinical follow-up information was obtained in 60 cases. The outcome was generally benign; the 16 asymptomatic patients remained well; 17 others had complete remission of symptoms, 22 had persistent symptoms, though half had partial improvement; 4 patients had progressive disease despite treatment, but only 1 patient died (of bilateral pneumothoraces complicating severe fibrosis). The more severe manifestations were found in young men, who had a higher incidence of pneumothorax, fibrosis and honeycombing, and diabetes insipidus. Many previously reported cases have had a less favorable outcome; milder cases of primary pulmonary histiocytosis have probably been overlooked in the past. In this series the prognostic value of histologic, clinical, or radiologic findings was limited. The diagnosis can often be strongly suggested radiologically, though infectious granulomata must be excluded; it is arguable whether exclusion of sarcoidosis is clinically important. The effecti...Continue Reading

Citations

Nov 14, 1997·Clinical Reviews in Allergy & Immunology·S MurinS J Reilly
Jan 6, 2005·European Radiology·Katharina Marten, David M Hansell
May 15, 2013·Frontiers of Medicine·Jay H RyuKaifeng Xu
Apr 1, 1991·Seminars in Roentgenology·D P Naidich
Jun 16, 2004·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M Aricò
Dec 7, 2002·European Journal of Radiology·Wallace T Miller
Jul 15, 2003·Respirology : Official Journal of the Asian Pacific Society of Respirology·Nicole S L GohGraeme N Brodie
Jul 31, 1986·The New England Journal of Medicine
Jul 6, 2000·The New England Journal of Medicine·R VassalloA H Limper
Feb 15, 2002·The New England Journal of Medicine·Robert VassalloAndrew H Limper
May 9, 2001·The American Journal of Surgical Pathology·S A YousemL M Weiss
Dec 5, 1997·Journal of Computer Assisted Tomography·Y KimJ G Im
Jan 14, 2009·Southern Medical Journal·Chirag Choudhary, Rendell W Ashton
Apr 1, 1988·Archives of Disease in Childhood·H P McDowellJ Martin
Apr 19, 2000·Thorax·A TaziA J Hance
Jun 30, 2007·Thorax·Jean-François Cordier
Aug 30, 2007·Thorax·Gregory P CosgroveKevin K Brown
Jun 25, 1998·American Journal of Respiratory and Critical Care Medicine·A TaziA J Hance
Jan 5, 2000·American Journal of Respiratory and Critical Care Medicine·M FartoukhG Simonneau
Nov 27, 2002·American Journal of Respiratory and Critical Care Medicine·Marianne KambouchnerPaul Soler
Nov 27, 2002·American Journal of Respiratory and Critical Care Medicine·Jeffrey L Myers, Marie-Christine Aubry
Mar 21, 2012·Orphanet Journal of Rare Diseases·Harpreet S SuriRobert Vassallo
Jul 17, 2008·Drugs·Rajesh R PatelRobert Vassallo
Apr 22, 2004·Internal Medicine·Masaru SuzukiMitsuru Oguri
Jan 1, 2008·The Libyan Journal of Medicine·W H IbrahimM Al-Maslamani
May 15, 2004·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Gerald F AbbottJeffrey R Galvin
Oct 15, 2003·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M AricòC Danesino
Oct 1, 1993·Journal of General Internal Medicine·R C St JohnE R Pacht
May 15, 2007·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Yeon Joo JeongWoon Jung Kwon
Jul 25, 2006·The British Journal of Radiology·C J DasM P Baruah

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