Epicardial adipose tissue in patients with heart failure.

Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance
Christina DoeschTheano Papavassiliu

Abstract

The aim of this study was to evaluate the extent of epicardial adipose tissue (EAT) and its relationship with left ventricular (LV) parameters assessed by cardiovascular magnetic resonance (CMR) in patients with congestive heart failure (CHF) and healthy controls. EAT is the true visceral fat deposited around the heart which generates various bioactive molecules. Previous studies found that EAT is related to left ventricular mass (LVM) in healthy subjects. Further studies showed a constant EAT to myocardial mass ratio in normal, ischemic and hypertrophied hearts. CMR was performed in 66 patients with CHF due to ischemic cardiomyopathy (ICM), or dilated cardiomyopathy (DCM) and 32 healthy controls. Ventricular volumes, dimensions and LV function were assessed. The amount of EAT was determined volumetrically and expressed as mass indexed to body surface area. Additionally, the EAT/LVM and the EAT/left ventricular remodelling index (LVRI) ratios were calculated. Patients with CHF had less indexed EAT mass than controls (22 +/- 5 g/m2 versus 34 +/- 4 g/m2, p < 0.0001). In the subgroup analysis there were no significant differences in indexed EAT mass between patients with ICM and DCM (21 +/- 4 g/m2 versus 23 +/- 6 g/m2, p = 0.14). ...Continue Reading

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Citations

Sep 15, 2011·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Dudley J PennellSanjay K Prasad
Nov 20, 2012·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Dudley J PennellSanjay K Prasad
Jun 3, 2014·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Ning HuaJames A Hamilton
May 14, 2011·The American Journal of Cardiology·Tuba KhawajaP Christian Schulze
May 29, 2012·International Journal of Cardiology·Yung-Kuo LinYi-Jen Chen
Oct 24, 2014·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Tuba KhawajaP Christian Schulze
Apr 26, 2014·Heart·Marit GranérMarja-Riitta Taskinen
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Aug 3, 2018·European Journal of Heart Failure·Gijs van WoerdenMichiel Rienstra
Mar 7, 2014·Journal of the American Heart Association·Timothy P Fitzgibbons, Michael P Czech
Nov 7, 2019·European Journal of Heart Failure·Cho-Kai WuLian-Yu Lin
Dec 21, 2018·Journal of the American Heart Association·Nitesh NerlekarThomas H Marwick
Apr 18, 2013·Current Opinion in Cardiology·Niki KatsikiAnthony S Wierzbicki
Apr 18, 2017·Methodist DeBakey Cardiovascular Journal·Yang WuTuo Deng
Nov 30, 2019·Clinical Science·Sarah R AnthonyMichael Tranter
Jun 11, 2020·Therapeutic Advances in Endocrinology and Metabolism·Regitse Højgaard ChristensenPeter Godsk Jørgensen
May 31, 2017·Journal of Cellular and Molecular Medicine·Santiago RouraAntoni Bayes-Genis
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May 15, 2021·Heart·Sarah L AytonAlastair J Moss
Jul 13, 2020·JACC. Heart Failure·Thomas M GorterDirk J van Veldhuisen

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