Epicardial and endocardial activation during sustained ventricular tachycardia in man

Circulation
L N HorowitzA H Harken

Abstract

Ventricular activation during ventricular tachycardia was studied by intraoperative epicardial and endocardial mapping in 21 patients with coronary artery disease and previous myocardial infarction who underwent operation for recurrent ventricular tachycardia. Twenty-nine morphologically distinct tachycardias were mapped; 18 tachycardias had a right bundle branch block morphology and 11 had a left bundle branch block morphology. After cannulation for bypass, the tachycardias were induced and electrograms were recorded at 55-75 epicardial sites. After starting cardiopulmonary bypass, the infarction was incised and electrograms were recorded at 28-55 left ventricular endocardial sites during ventricular tachycardia. All mapping data were analyzed with three simultaneously recorded ECG lead and two reference electrograms. Earliest activation in all tachycardias occured on the endocardial surface of the infarction. In each tachycardia, endocardial electrical activity was recorded before the onset of the QRS complex. Earliest epicardial activation in the 29 tachycardias occurred 10 msec after the onset of QRS complex. Epicardial breakthrough occurred on the right (19 tachycardias) as well as the left ventricle (10 tachycardias). We ...Continue Reading

References

Aug 1, 1975·The Annals of Thoracic Surgery·J H Wittig, J P Boineau
Mar 1, 1978·Circulation·M E JosephsonJ A Kastor
Mar 1, 1978·Circulation·M E JosephsonE N Moore
Sep 1, 1978·The American Journal of Cardiology·M E JosephsonA M Greenspan
Feb 1, 1976·Circulation Research·A L Wit, P F Cranefield
Feb 1, 1975·British Heart Journal·R A SpurrellD C Deuchar
Dec 1, 1973·The American Journal of Cardiology·A F GrahamD C Harrison
Jun 1, 1971·The American Journal of Cardiology·G S ThindH F Zinsser

❮ Previous
Next ❯

Citations

Oct 15, 1987·Experientia·B F Hoffman, K H Dangman
Jul 1, 1988·Journal of the American College of Cardiology·J J LangbergN B Schiller
Mar 1, 1988·Journal of the American College of Cardiology·W G StevensonT Klitzner
Mar 15, 1989·Journal of the American College of Cardiology·D M Cassidy, M E Cain
Oct 1, 1991·Journal of the American College of Cardiology·J M de BakkerP F Bakker de Wekker
Nov 15, 1992·Journal of the American College of Cardiology·S K KimberT C Chen
Jul 1, 1983·Journal of the American College of Cardiology·Y IesakaJ W Lister
Dec 1, 1984·Journal of the American College of Cardiology·J M MillerM E Josephson
Oct 1, 1984·Journal of the American College of Cardiology·E DownarM B Waxman
Dec 1, 1985·Journal of the American College of Cardiology·J M MillerM E Josephson
Nov 1, 1987·Journal of the American College of Cardiology·L HarrisI Parson
Apr 23, 1981·The New England Journal of Medicine·J A KastorM E Josephson
Apr 1, 1991·Pacing and Clinical Electrophysiology : PACE·J M DesaiP J Vogelsang
Feb 1, 1995·Pacing and Clinical Electrophysiology : PACE·C Nibley, J M Wharton
Jan 1, 1997·Pacing and Clinical Electrophysiology : PACE·J K TriedmanE P Walsh
Feb 1, 1997·Pacing and Clinical Electrophysiology : PACE·G R SimonsA Natale
Aug 30, 2000·Pacing and Clinical Electrophysiology : PACE·S C Krishnan, M E Josephson
Jun 24, 2014·Revista Española De Cardiología·Pablo Avila, Angel Arenal
Jan 1, 1989·Scandinavian Journal of Thoracic and Cardiovascular Surgery·A MangschauO Geiran
Feb 27, 2014·Indian Heart Journal·Olujimi A AjijolaKalyanam Shivkumar
Aug 6, 2009·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Haris M Haqqani, Francis E Marchlinski
Jul 5, 2008·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Frank Bogun
Oct 1, 1985·Journal of Electrocardiology·S N ErnéH P Lehmann
Oct 3, 2003·Journal of Cardiovascular Electrophysiology·Mark E Josephson
Dec 1, 1982·The American Journal of Medicine·S C Vlay, P R Reid
Oct 1, 1992·IEEE Transactions on Bio-medical Engineering·T L WonnellJ J Langberg
Jan 1, 1989·Progress in Cardiovascular Diseases·P A HallV F Froelicher
Jun 1, 1983·American Journal of Surgery·A H Harken, M E Josephson
Feb 1, 1984·The American Journal of Cardiology·G H BardyR E Ideker

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.