PMID: 591066Dec 1, 1977

Epidemic caprine keratoconjunctivitis: recovery of Mycoplasma conjunctivae and its possible role in pathogenesis

Infection and Immunity
E J BaasM F Barile

Abstract

Clinical, microbiological, serological, histological, and therapeutic aspects of two separate outbreaks of caprine keratoconjunctivitis are described. The disease was characterized by a high rate of contagion, rapid onset, intense lacrimation, conjunctival hyperemia, and corneal opacity with neovascularization. In addition, many of the animals developed respiratory illness during the second epidemic. The only organism consistentlyisolated was Mycoplasma conjunctivae. A total of 23 strains were isolated from 18 inflamed conjunctivae, one normal conjunctiva, and the nasal secretions of four goats with concomitant respiratory illness. The convalescent sera of goats in the first outbreak had neutralizing antibody titers to M. conjunctivae that ranged from 1:32 to 1:256. In the milder second outbreak the antibody titers ranged from 1:4 to 1:32 in animals with only ocular disease and from 1:4 to 1:64 in animals with only respiratory disease. Whereas little change was noted in antibody titers of goats with only localized eye disease, 43% of the goats with respiratory disease showed significant fourfold rises. The histological picture was consistent with acute corneal infection. Animals requiring antibiotic treatment appeared to respon...Continue Reading

Citations

May 1, 1996·Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B·D MayerW Meier
May 21, 2017·Applied and Environmental Microbiology·Xavier Fernández-AguilarJorge Ramón López-Olvera
Jan 1, 1992·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·A J DaMassaD L Brooks
Oct 1, 1988·The Veterinary Quarterly·E A ter LaakD J Houwers
Jan 1, 2014·Veterinary Record Open·Francesca BonelliMicaela Sgorbini

Related Concepts

Antibodies, Bacterial
Structure of Bulbar Conjunctiva
Goat
Keratoconjunctivitis
Mycoplasma putrefaciens
Oxytetracycline, (5 beta)-Isomer
Aerosporin

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