PMID: 591067Dec 1, 1977

Epidemic caprine keratoconjunctivitis: experimentally induced disease with a pure culture of Mycoplasma conjunctivae

Infection and Immunity
S L TrotterM F Barile


The induction of caprine keratoconjunctivitis by the subconjunctival inoculation of a cloned culture of Mycoplasma conjunctivae is described. The clinical course of the experimental disease was similar to that noted in naturally occurring outbreaks of "pink-eye" among goats, and biopsies of inflamed conjunctivae showed similar histological response. M. conjunctivae was consistently recovered from the inflamed conjunctival tissues of inoculated animals that developed ocular disease, thus fulfilling Koch's postulates and establishing this organism as an etiological agent of caprine keratoconjunctivitis. Immunological studies suggested that cellular immune mechanisms may play a role in protecting animals from disease produced by this mycoplasma.


May 1, 1996·Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B·D MayerW Meier
Apr 5, 2003·Applied and Environmental Microbiology·Luc BelloyJoachim Frey
May 21, 2017·Applied and Environmental Microbiology·Xavier Fernández-AguilarJorge Ramón López-Olvera
Jan 1, 1992·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·A J DaMassaD L Brooks
Oct 1, 1988·The Veterinary Quarterly·E A ter LaakD J Houwers
Oct 11, 2017·PloS One·Xavier Fernández-AguilarJorge Ramón López-Olvera

Related Concepts

Antibodies, Bacterial
Structure of Bulbar Conjunctiva
Lymphocyte Activation
Mycoplasma putrefaciens

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