PMID: 9555756Apr 29, 1998Paper

Epidemic of pediatric deaths from acute renal failure caused by diethylene glycol poisoning. Acute Renal Failure Investigation Team

JAMA : the Journal of the American Medical Association
K L O'BrienK Denerville

Abstract

Contaminated pharmaceutical products can result in substantial morbidity and mortality and should be included in the differential diagnosis of deaths of unknown origin. To investigate an outbreak of deaths among children from acute renal failure in Haiti to determine the etiology and institute control measures. Case-control study, cohort study, and laboratory toxicologic evaluation. Pediatric population of Haiti. Cases were defined as Haitian residents younger than 18 years with idiopathic anuria or severe oliguria for 24 hours or longer. Febrile hospitalized children without renal failure were enrolled as control subjects. The odds of exposure to suspected etiologic agents among cases and controls. We identified 109 cases of acute renal failure among children. The clinical syndrome included renal failure, hepatitis, pancreatitis, central nervous system impairment, coma, and death. Of 87 patients with follow-up information who remained in Haiti for treatment, 85 (98%) died; 3 (27%) of 11 patients transported to the United States for intensive care unit management died before hospital discharge. A locally manufactured acetaminophen syrup was highly associated with disease (odds ratio, 52.7; 95% confidence interval, 15.2-197.2). ...Continue Reading

Citations

Sep 24, 2005·Archives of Disease in Childhood·S A BeggsM D Reed
Mar 14, 2008·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Joshua G SchierUNKNOWN Panama Follow-Up Investigation Workgroup
May 29, 2008·World Journal of Gastroenterology : WJG·Bing-Liang LinZhi-Liang Gao
Oct 25, 2008·Bulletin of the World Health Organization·E Danielle RentzCarol Rubin
Oct 31, 2009·Globalization and Health·Habibat A GarubaAnna M Huisman
Oct 12, 2010·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Joshua G SchierMichael A McGeehin
Mar 19, 2011·Tobacco Control·Jean-François EtterThomas Eissenberg
May 8, 2000·Indian Journal of Pediatrics·A Bagga
Jan 17, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Rosamund Modupe AkuseOlugbenga Awobusuyi
Jun 10, 2010·Toxicological Sciences : an Official Journal of the Society of Toxicology·Lauren M BesenhoferKenneth E McMartin
Aug 2, 2011·Toxicological Sciences : an Official Journal of the Society of Toxicology·Lauren M BesenhoferKenneth E McMartin
Aug 23, 2011·Toxicological Sciences : an Official Journal of the Society of Toxicology·Greg M LandryKenneth E McMartin
Jul 15, 2009·Journal of Public Health Policy·Joshua G SchierMichael A McGeehin
Oct 19, 2013·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·J R SchwartzbordD L Brown
Sep 17, 2008·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Xiao M PengGui Hua Chen
Nov 26, 2013·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·J G SchierW D Flanders
Jul 26, 2008·Journal of the American Pharmacists Association : JAPhA·Ronald J Ziance
May 23, 2012·The Journal of Sexual Medicine·Maria Cristina GaudianoLuisa Valvo
Oct 23, 2008·Translational Research : the Journal of Laboratory and Clinical Medicine·Jai Moo ShinJeffrey A Kraut
Nov 21, 2007·The Journal of Emergency Medicine·Jeanna M MarraffaMichael J Hodgman
Jul 18, 2008·Tropical Medicine & International Health : TM & IH·J-M CaudronJ Pinel
Jan 21, 2014·Journal of Anatomy·Erich Brenner
Aug 26, 2006·The Lancet Infectious Diseases·Paul N NewtonNicholas J White
Sep 21, 2005·Forensic Science International : Synergy·L J Schep, R J Slaughter
Aug 6, 2015·Journal of Food Science and Technology·Chikkappa Udagani, Thimmasandra Narayan Ramesh
Dec 30, 2014·Toxicology and Applied Pharmacology·Greg M LandryKenneth E McMartin
May 15, 2012·Advances in Chronic Kidney Disease·Gaurav RamanBernard G Jaar
Jan 12, 2017·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Corie N RobinsonKenneth E McMartin
Apr 22, 2015·The American Journal of Tropical Medicine and Hygiene·Abigail A Weaver, Marya Lieberman
Jul 13, 2000·Academic Medicine : Journal of the Association of American Medical Colleges·J C Kolars
Oct 7, 2018·Tropical Medicine & International Health : TM & IH·Mohammad Sofiqur RahmanKazuko Kimura
Aug 17, 2006·Pediatric Emergency Care·Manish M PatelMartin G Belson
Jan 24, 2008·Nature Clinical Practice. Nephrology·Jorge CerdáRajasekara M Chakravarthi
Jun 27, 2003·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Ian WongAlexander Florence
Nov 30, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Jeffrey A Kraut, Ira Kurtz
Oct 16, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Didier PortillaTod Ibrahim
Jun 7, 2007·The Journal of Antimicrobial Chemotherapy·Theodore KelesidisMatthew E Falagas
Jul 24, 2003·Reviews on Environmental Health·Michael Gracey
Jan 4, 2001·Pancreas·V Khurana, J S Barkin
Feb 24, 2007·Journal of Paediatrics and Child Health·Yashwant Sinha, Noel E Cranswick
Jul 18, 2003·Birth Defects Research. Part B, Developmental and Reproductive Toxicology·Tracey Zoetis, Mark E Hurtt
May 15, 2003·Quality Assurance : QA·Robert S DeWoskin
Nov 10, 2015·British Journal of Clinical Pharmacology·Kenneth McMartinKnut Erik Hovda

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