Epidemic Pseudomonas aeruginosa serotype O16 bacteremia in hematology-oncology patients.

Journal of Clinical Microbiology
H RichetP H Lagrange

Abstract

From 1 August 1978 through 31 December 1982, 98 hematology-oncology patients had positive cultures for Pseudomonas aeruginosa serotype O16; 22 of these patients developed bacteremia, and this bacteremia was associated with the occurrence of extensive perineal cellulitis in 10 patients (45.5%). Seventeen bacteremic patients died. The epidemic strain differed from other P. aeruginosa organisms isolated at the hospital by its resistance to all antibiotics available at that time (ticarcillin, piperacillin, azlocillin, tobramycin, ceftizoxime, ceftriaxone, moxalactam, ceftazidime, and fosfomycin). Univariate analysis showed the following factors to be significantly associated with P. aeruginosa O16 bacteremia: the severity of granulocytopenia at the time of the bacteremia, more days with fever, the administration of ticarcillin or an aminoglycoside, the receipt of a greater number of antimicrobial agents for a longer period of time before documentation of the bacteremia, and the occurrence of cellulitis. Logistic regression analysis showed that duration of fever, duration of bacteremia, and the number of antimicrobial agents administered before documentation of the bacteremia were the best predictors of P. aeruginosa O16 bacteremia....Continue Reading

References

Jul 1, 1973·The Journal of Trauma·B G MacMillarM P Maley
Dec 1, 1971·The Journal of Infectious Diseases·J A ShulmanC E Hough
Mar 1, 1981·The Journal of Hospital Infection·P W Smith, P G Rusnak
Mar 1, 1980·The Journal of Hospital Infection·D C Shanson
Dec 1, 1984·The Journal of Infectious Diseases·B OlsonS A Kabins

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Citations

Jul 1, 1993·European Journal of Epidemiology·A GrigisT Barbui
Aug 21, 2002·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Geir BukholmNils Smith-Erichsen
Apr 1, 1990·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·W KernG Döring
May 1, 1990·Journal of Clinical Microbiology·P V Liu, S Wang

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