Epidemiologic Factors, Clinical Presentation, Causes, and Outcomes of Liver Abscess: A 35-Year Olmsted County Study

Mayo Clinic Proceedings. Innovations, Quality & Outcomes
Ayush SharmaNathan Cummins

Abstract

To report the changing incidence, clinical presentation, microbiologic spectrum, and outcomes of pyogenic liver abscess (PLA) in Olmsted County, Minnesota, over the past 35 years. The Rochester Epidemiology Project was used to identify residents with PLA from January 1, 1980, through December 31, 2014. The study included all patients older than 18 years, with the diagnosis of PLA confirmed through radiographic review and microbiologic cultures. In total, 72 patients received a diagnosis of PLA from 1980 through 2014. The age-adjusted incidence for men was 3.92 cases per 100,000 person-years (95% CI, 2.76-5.09 cases per 100,000 person-years) compared with 1.87 cases per 100,000 person-years (95% CI, 1.15-2.59 cases per 100,000 person-years) for women. Incidence was higher in the period from January 1, 2001, through December 31, 2014, than in the period from January 1, 1980, through December 31, 2000, for women (incidence rate ratio [IRR], 3.8; 95% CI, 1.43-10.09; P=.007) but not for men (IRR, 0.99; 95% CI, 0.55-1.76; P=.96). Fifteen additional patients had postintervention PLA (1980-2000: n=3 of 29 [10.3%] vs 2001-2015: n=12 of 58 [20.6%]). A significant association was seen between age- and sex-adjusted incidence rates of PLA a...Continue Reading

References

Dec 1, 1990·Annals of Surgery·G D BranumW C Meyers
Mar 1, 1996·Mayo Clinic Proceedings·L J Melton
May 1, 1996·Annals of Surgery·C J HuangG D Zuidema
Apr 21, 1998·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·P S Hansen, H C Schønheyder
Mar 13, 1999·The Australian and New Zealand Journal of Surgery·M S BarakateD M Sheldon
May 9, 2001·World Journal of Surgery·E vanSonnenbergH B D'Agostino
Jun 27, 2001·American Journal of Surgery·J A Alvarez PérezJ I Jorge
Aug 9, 2002·Journal of Gastroenterology and Hepatology·Wai-Man WongChing Lung Lai
Nov 28, 2002·QJM : Monthly Journal of the Association of Physicians·A H MohsenM W McKendrick
Nov 20, 2004·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Gilaad G KaplanKevin B Laupland
Dec 4, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Joseph RahimianRobert S Holzman
May 11, 2005·Alimentary Pharmacology & Therapeutics·P JepsenH T Sørensen
Nov 23, 2006·AJR. American Journal of Roentgenology·Antonio GiorgioGiovanna Ferraioli
Dec 11, 2007·American Journal of Infection Control·Jane D SiegelUNKNOWN Healthcare Infection Control Practices Advisory Committee
Mar 14, 2008·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·G FerraioliC Filice
Oct 2, 2008·Emerging Infectious Diseases·Feng-Chiao TsaiJin-Town Wang
Oct 25, 2008·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Alicia I HidronUNKNOWN Participating National Healthcare Safety Network Facilities
Oct 15, 2009·The American Journal of Gastroenterology·Ning-Ping FooHow-Ran Guo
Nov 6, 2009·The American Journal of Gastroenterology·Liisa MeddingsGilaad G Kaplan
Oct 27, 2012·The Lancet Infectious Diseases·L Kristopher SiuFeng-Yee Chang
Dec 3, 2014·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Yung-Chun ChenZhi-Yuan Shi

❮ Previous
Next ❯

Methods Mentioned

BETA
percutaneous aspiration
surgical resection

Software Mentioned

Research Electronic Data Capture
SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.