PMID: 2483071Jan 1, 1989Paper

[Epidemiologic situation of rubella in Italy 20 years after the introduction of the vaccine].

Annali di igiene : medicina preventiva e di comunità
M G Galli

Abstract

Rubella vaccination has been introduced in USA in 1969: it was addressed to all the newborn and to women in childbearing age. In 1970 it was offered in Europe to schoolgirls aged 11-14 and to women of reproductive age. The purposes were identical--namely to eliminate the incidence of CRS--in spite of the different strategies adopted: in fact the American vaccination programme tried to reach this aim in eradicating the disease, while in Europe special attention was given to the possibility of reduce morbidity in childbearing age. After 20 years we can try to verify if these objects have been attained. Recent data (MMWR, 1987) show that rubella morbidity in USA has dropped considerably (incidence rate in 1966 = 24.3; in 1986 = 0.2) and incidence rate for CRS decreased accordingly from 0.90 (1969) to 0.32. Nevertheless we must underline that 47.5% of cases in USA from 1984 to 1986 were seen in person older than 20, and serologic studies have shown that infection susceptibility, in the postpuberal population, is the same that in prevaccinal era (10-20%). Many evaluation of efficacy of vaccinal strategies have been carried out in Europe, always showing a smaller number of women of reproductive age susceptible toward infection, toget...Continue Reading

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