PMID: 6971272Dec 1, 1980Paper

Epidemiological aids to clinical decision making in primary open angle glaucoma

International Ophthalmology
R P Crick, J Daubs

Abstract

We have described the epidemiological analysis of one aspect of the King's College Hospital computerized data base; namely initial intraocular pressure as an indicator of visual field loss. The methods involved the use of the four-fold table to determine sensitivity and specificity at different pressure levels. From these results (1) the changes in the pre and post test probability of field loss are calculated and (2) a 'sensitivity/specificity trade off curve' or 'decision curve' is constructed. In this way the optimal 'cut-off level' or 'operating point' for a population of specific type and composition can be determined. The factors concerned in decision making are always complex but such an approach allows a rational and quantifiable alternative to reliance on clinical impression and intuition. The results have significance in relation to decisions on the management of patients and on population screening programmes for glaucoma.

References

Jul 1, 1977·Archives of Ophthalmology·Y KitazawaK Nishioka

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Citations

Dec 1, 1980·International Ophthalmology·J G Daubs, R P Crick
Jan 1, 1984·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·J G Daubs
Dec 1, 1985·The British Journal of Ophthalmology·J E RossP G Emmerson
Jan 1, 1990·The British Journal of Ophthalmology·R VogelC J Bulpitt
Oct 1, 2009·Clinical & Experimental Ophthalmology·Stephen Vernon
Jan 1, 1992·International Journal of Cardiac Imaging·S BhattacharyaA Lahiri
Sep 5, 1995·Journal of Interventional Cardiology·D T Gray

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