Epidemiological analysis of maternal lipid levels during the second trimester in pregnancy and the risk of adverse pregnancy outcome adjusted by pregnancy BMI

Journal of Clinical Laboratory Analysis
Chao-Yan Yue, Chun-Mei Ying

Abstract

Pregnancy is accompanied by profound changes in lipid metabolism. We aimed to assess whether effects of second trimester body mass index and maternal lipid concentrations are associated with an increased risk of adverse pregnancy outcomes. We investigated the serum levels of maternal lipids during the second trimester in pregnancy, and analyzed associations between the lipid levels and the risk of adverse pregnancy outcome. Seven hundred and seventy-four pregnant women were enrolled in this study between February 2016 and June 2016. Multivariate logistic regression analysis was conducted to estimate the relative risk between maternal lipids and adverse pregnancy outcome. Compared with the control group, during the second trimester of pregnancy, BMI, TG, and Lp(a) were risk factors for gestational diabetes mellitus; middle trimester pregnancy BMI, Lp(a), and APO-B were risk factors for pre-eclampsia; second trimester BMI and TG/HDL-C were risk factors for macrosomia; age and Lp(a) were uterine atony postpartum hemorrhage risk factors, while APO-AI was a protective factor of uterine inertia and postpartum hemorrhage; second trimester BMI, TCH, Lp(a), and TG/HDL-C were risk factors for fetal distress, while parity was a protective...Continue Reading

References

Feb 1, 1990·The Australian & New Zealand Journal of Obstetrics & Gynaecology·K UmapathysivamW R Jones
May 9, 2000·The American Journal of Clinical Nutrition·J C King
Jan 11, 2003·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Janice RymerM Crook
Jul 6, 2004·American Journal of Hypertension·Daniel A EnquobahrieDavid A Luthy
Nov 10, 2004·Medical Hypotheses·G T R MantenArie Franx
Jul 29, 2005·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Gokhan BayhanZeki Akkus
Apr 11, 2006·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Tracey L Weissgerber, Larry A Wolfe
Apr 25, 2007·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Gwendolyn T R MantenArie Franx
Jul 28, 2009·American Journal of Obstetrics and Gynecology·Arnon WiznitzerLena Novack
Feb 24, 2010·Obstetrics and Gynecology·Monique M HeddersonAssiamira Ferrara
May 10, 2011·Bangladesh Medical Research Council Bulletin·Saila ParvinIbrahim Siddique
Aug 11, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Neslihan BukanBanu Cayci
Oct 12, 2011·The Journal of International Medical Research·B DemirG Toprak
Nov 21, 2012·Journal of cardiology·Angela E Fanshawe, Michael Ibrahim
Dec 25, 2012·Clinica Chimica Acta; International Journal of Clinical Chemistry·Izabella C R dos Santos-WeissGeraldo Picheth
Jan 23, 2013·The Journal of Clinical Endocrinology and Metabolism·Barbara J MeyerDilys J Freeman
Feb 13, 2013·Archives of Gynecology and Obstetrics·Turgay EmetAyşe Filiz Avşar
Apr 4, 2013·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·K HodsonR Taylor
Apr 10, 2013·The Journal of International Medical Research·A SkvarcaA Janez
Feb 3, 2015·BJOG : an International Journal of Obstetrics and Gynaecology·D R FariasG Kac

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