Epidemiological characteristics and societal burden of varicella zoster virus in the Netherlands.

BMC Infectious Diseases
Jorien G J PierikMaarten J Postma

Abstract

Varicella and herpes zoster are both caused by varicella zoster virus (VZV) infection or reactivation and may lead to complications associated with a (severe) societal burden. Because the epidemiology of VZV-related diseases in the Netherlands remains largely unknown or incomplete, the main objective of this study was to study the primary care incidence, associated complications and health care resource use. We investigated the incidence of VZV complications in the Dutch general practitioner (GP) practices and pharmacies in a retrospective population-based cohort study (2004-2008) based on longitudinal GP data including free text fields, hospital referral and discharge letters from approximately 165,000 patients. The average annual incidence of varicella GP-consultations was 51.5 per 10,000 (95% CI 44.4-58.7) overall; 465.5 per 10,000 for 0-1 year-olds; 610.8 per 10,000 for 1-4 year-olds; 153.5 per 10,000 for 5-9 year-olds; 8,3 per 10,000 for >10 year olds. When only ICPC coded diagnoses were analyzed the incidence was 27% lower. The proportion of complications among varicella patients was 34.9%. Most frequently complications were upper respiratory tract infections. Almost half of the varicella patients received medication. The...Continue Reading

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Dec 29, 2012·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Bernhard UltschOle Wichmann
Jul 23, 2013·The Journal of Infection·Dahlia WeitzmanVarda Shalev
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Mar 3, 2021·Human Vaccines & Immunotherapeutics·Désirée van OorschotBarbara Yawn

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