Epidemiological, clinical, and biochemical characteristics of Saudi patients with nonalcoholic fatty liver disease: a hospital-based study.

Annals of Saudi Medicine
Waleed Al-hamoudiAyman Abdo

Abstract

The estimated prevalence of nonalcoholic fatty liver disease (NAFLD) in Saudi Arabia is 7% to 10%. Despite the high prevalence of risk factors including diabetes, obesity, and hyperlipidemia, no recent epidemiological studies have measured the disease burden. We aimed to determine the characteristics of Saudi NAFLD patients attending a university hospital, and study factors affecting alanine aminotransferase (ALT) levels. A prospective study among patients referred for ultrasonography in King Khalid University Hospital in Riyadh, Saudi Arabia from February to May 2009. NAFLD was defined as an appearance of fatty liver on routine abdominal ultrasound in the absence of coexisting liver disease and alcohol consumption. Patients were classified into normal and high ALT (ALT >60 U/L) level groups for analysis. The prevalence of NAFLD was 16.6% (218/1312). Patients with normal ALT had the mean (SD) age of 45.9 (10.6) years and the mean body mass index of 34.5 (7.9) kg/m2. Forty percent of the 151 patients with normal ALT had diabetes, 66.2% were obese, and 29.1% had hypertension. Forty-three patients (23%) had high ALT levels. These patients had significantly lower age (P=.003) and fasting blood sugar (P=.03) than the normal ALT grou...Continue Reading

References

May 1, 1988·Japanese Journal of Medicine·H NomuraM Goto
Jan 15, 2000·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·H Cortez-PintoM C De Moura
Jan 22, 2000·Annals of Internal Medicine·S BellentaniC Tiribelli
Apr 12, 2001·Seminars in Liver Disease·Y Falck-YtterA J McCullough
Sep 6, 2002·The New England Journal of Medicine·J Christian Bode
Sep 19, 2002·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·U L MathiesenG Bodemar
Jan 4, 2003·Gastroenterology·Jeanne M Clark, Anna Mae Diehl
Jun 18, 2003·The American Journal of Gastroenterology·Jeanne M ClarkAnna Mae Diehl
Jun 9, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Fabrice LainéYves Deugnier
Jun 9, 2005·Gastroenterology·Vlad RatziuUNKNOWN LIDO Study Group
Jan 12, 2008·World Journal of Gastroenterology : WJG·R Scott RectorJamal A Ibdah

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Citations

Sep 26, 2015·Journal of Digestive Diseases·Münevver DemirHans-Michael Steffen
Jun 15, 2017·Expert Review of Gastroenterology & Hepatology·Ching-Sheng Hsu, Jia-Horng Kao
Jun 30, 2018·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Khalid AlswatHomie Razavi
Nov 15, 2018·International Journal of Environmental Research and Public Health·Abdullah A AlsabaaniSuliman M Al Humayed
Apr 3, 2016·Digestive Diseases and Sciences·Zaki A SherifHassan Ashktorab
Apr 29, 2020·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Faisal A AlsaifWaleed K Al-Hamoudi
Oct 24, 2014·World Journal of Gastroenterology : WJG·Marco BertolottiPaola Loria
Jul 14, 2016·Surgical Endoscopy·Tamadar AldoheyanHisham Al-Khalidi
Jun 1, 2017·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Abdullah Omar Al HoussienAbdulaziz Al-Hawass
Jun 19, 2013·BMC Complementary and Alternative Medicine·Salem S Al-RejaieMohamed M Hafez
Sep 21, 2021·Expert Opinion on Pharmacotherapy·Ching-Sheng Hsu, Jia-Horng Kao

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Methods Mentioned

BETA
enzyme-linked immunosorbent assay
biopsies
biopsy

Software Mentioned

Stata

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