Epidemiological Profile of Acute Viral Encephalitis

Indian Journal of Pediatrics
Rajesh KumarSamrendra Narayan

Abstract

To study the etiology and clinico-epidemiological profile of acute viral encephalitis in children with acute encephalitis syndrome (AES). An observational study including 100 patients fulfilling the criteria for AES was conducted in children of age group 1 mo - 16 y. Viral isolation was done on RD cells, HEp-2 cells and Vero cells from the cerebrospinal fluid samples of suspected viral encephalitis (VE) cases. An enzyme immunoassay for IgM antibodies was performed for measles, mumps, Varicella zoster virus (VZV), Herpes simplex virus 1 (HSV1) and Japanese encephalitis virus (JEV). Multiplex polymerase chain reaction (PCR) was done for Cytomegalovirus, Epstein Barr virus (EBV), HSV1 & 2, VZV, Enterovirus, Parecho virus, Human Herpes virus (HHV 6, 7) and Parvovirus B19. A micro neutralization test was performed for Enterovirus 71. Out of enrolled 100 patients, 73 were of probable viral encephalitis. HSV1 (31.50%) was the commonest virus followed by Adenovirus (10.95%), Parvovirus (2.73%), JE virus (1.36%), Enterovirus (1.36%), EBV (1.36%), and mixed infection with HSV & EBV (1.36%). HSV 1 caused significant morbidity in children. The common computed tomography (CT) findings were hypodensities in the fronto- parietal lobe followed...Continue Reading

References

Jul 26, 1990·The New England Journal of Medicine·R J Whitley
Jan 16, 1986·The New England Journal of Medicine·R J WhitleyS J Soong
Nov 5, 2002·Postgraduate Medical Journal·A Chaudhuri, P G E Kennedy
Feb 24, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·P G E Kennedy
Jul 29, 2004·Indian Journal of Pediatrics·Lalitha KabilanA P Dash
Dec 29, 2004·Lancet Neurology·Howard E Gendelman, Yuri Persidsky
Nov 17, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C A GlaserJ H Tureen
Nov 30, 2007·Pediatrics International : Official Journal of the Japan Pediatric Society·Ajit RayamajhiSunit Singhi
Sep 5, 2008·Indian Journal of Pediatrics·S A KarmarkarB K Y Chauhan
Jan 29, 2010·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Farzana K BeigShashi Khare
Apr 13, 2011·Current Opinion in Neurology·Israel Steiner
Oct 22, 2013·BMC Neurology·Abhinbhen SarayaThiravat Hemachudha
May 27, 2014·Japanese Journal of Infectious Diseases·Parul JainG Arun Kumar
Jan 24, 2016·Indian Journal of Pediatrics·Renu SutharPratibha Singhi
Aug 30, 2016·Annals of Indian Academy of Neurology·Sheffali GulatiMadhulika Kabra

❮ Previous
Next ❯

Citations

Mar 24, 2018·Indian Journal of Pediatrics·Biswaroop Chakrabarty
Nov 7, 2020·Brain and Behavior·Daiva RadzišauskienėRūta Mameniškienė
Aug 19, 2021·Movement Disorders Clinical Practice·Annu AggarwalMohit Bhatt

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Acute Hemorrhagic Leukoencephalitis

Acute hemorrhagic leukoencephalitis is a rare form of acute disseminated encephalomyelitis characterized by acute inflammation in the brain and spinal cord that causes demyelination and bleeding. It is often fatal, although treatment with immunosuppressives and plasma exchange can be helpful. Find the latest research on acute hemorrhagic leukoencephalitis here.

Related Papers

Japanese Journal of Infectious Diseases
Parul JainG Arun Kumar
Revista Da Sociedade Brasileira De Medicina Tropical
Diógenes RodriguesRodrigo Minuto Paiva
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Ugo K IhekwabaMichael W McKendrick
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Maria CiardiSalvatore Delia
© 2022 Meta ULC. All rights reserved