Abstract
Since 1986, penicillin non-susceptible pneumococci (PNSP) have been found in the Czech Republic. As documented by a nationwide study, the proportion of invasive strains with reduced susceptibility to penicillin has fluctuated around 5 % in the past decade. Although the level of resistance to penicillin remains stable, the contribution of different capsular serotypes among the PNSP population varies. Whereas serotype 19A was predominantly associated with penicillin resistance until 1997, serotype 9V became most common among PNSP strains in 1998. In a collection of PNSP strains (n=225) isolated from 2000 to 2002, the most frequent serotype was 9V (n=91, 40.4 %), followed by 19F (n=30, 13.3 %) and 14 (n=25, 11.5 %). PFGE and multilocus sequence typing were used to characterize a set of PNSP of the currently predominant serotypes 9V (n=42), 14 (n=15) and 19F (n=14). The Spain(9V)-3 clone [sequence type (ST) 156] was responsible for a large proportion (100 % of serotype 9V strains, n=42; 93.3 % of serotype 14 strains, n=14) of the analysed strains. A representative of the Taiwan(19F)-14 clone (ST 236) was also recovered in the Czech Republic (a single isolate of serotype 19F). These findings confirm the spread of the major penicilli...Continue Reading
References
Sep 1, 1991·Molecular Microbiology·T J CoffeyJ M Musser
Aug 1, 1991·The Journal of Infectious Diseases·R MuñozB G Spratt
Mar 1, 1995·Microbiology·A M GascA M Sicard
Aug 1, 1993·Journal of Clinical Microbiology·U B Sørensen
Jul 1, 1993·The Journal of Infectious Diseases·S SoaresA Tomasz
Apr 1, 1995·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·T J CoffeyB G Spratt
Apr 1, 1995·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·A M FigueiredoA Tomasz
Jul 1, 1995·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·F Baquero
Oct 6, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J H SongC H Pai
Nov 18, 1998·Journal of Clinical Microbiology·Z Y ShiB G Spratt
Dec 10, 1998·Microbiology·Mark C Enright, Brian G Spratt
Aug 27, 1999·Microbiology·T J CoffeyB G Spratt
Sep 17, 1999·Journal of Clinical Microbiology·M C EnrightB G Spratt
May 19, 2000·Antimicrobial Agents and Chemotherapy·A GiacomettiG Scalise
Jun 28, 2001·Journal of Clinical Microbiology·L McGeeK P Klugman
Oct 13, 2001·The Journal of Infectious Diseases·R Sá-LeãoH de Lencastre
Jan 5, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·S S RichterG V Doern
Feb 28, 2002·Journal of Medical Microbiology·Steven Obaro, Richard Adegbola
Sep 6, 2003·Journal of Clinical Microbiology·Robert E GertzBernard Beall
Nov 26, 2003·The Journal of Infectious Diseases·M Catherine McEllistremEllen R Wald
Feb 20, 2004·Journal of Bacteriology·Edward J FeilBrian G Spratt
Apr 15, 2004·International Journal of Antimicrobial Agents·Pavel CermákTomás Látal
May 14, 2004·The Journal of Antimicrobial Chemotherapy·Astrid BuxbaumUNKNOWN Austrian Bacterial Surveillance Network
Nov 20, 2004·The Journal of Infectious Diseases·Nurith PoratRon Dagan
Apr 9, 2005·Journal of Clinical Microbiology·I SerranoM Ramirez
Citations
Jul 24, 2007·Proceedings of the National Academy of Sciences of the United States of America·K SjöströmB Henriques-Normark
Sep 1, 2012·The Pediatric Infectious Disease Journal·Yu-Wen ChienKeith P Klugman
Feb 2, 2010·Emerging Infectious Diseases·Helena ZemlickovaBohumir Prochazka
Jun 12, 2008·Wiener klinische Wochenschrift·Vlastimil JindrákUNKNOWN Working Group on Monitoring Antimicrobial Resistance
Mar 21, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·H ZemlickováP Urbásková
Jun 2, 2018·Journal of Medical Microbiology·Helena ŽemličkováMatej Medvecký
Oct 17, 2008·Nature Reviews. Microbiology·Birgitta Henriques-NormarkStaffan Normark