PMID: 18206007Jan 22, 2008Paper

Epidemiological study on respiratory syncytial virus and its bronchopneumonia among children in Suzhou

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]
Xuelan ZhangXue-qiang Ji

Abstract

To probe the epidemiological trend of respiratory syncytial virus (RSV) and cellular immunological change of RSV bronchopneumonia among children in Suzhou in the past five years. 10,205 children with acute respiratory tract infection from January 2001 to December 2005 were enrolled into the study. Nasopharyngeal aspirates were obtained from the respiratory tract by aseptic vacuum aspiration. Direct immuno-fluorescence assay was employed to detect seven kinds of virus antigens including RSV antigen. CD3, CD4, CD8, CD19, CD16 and CD56 in peripheral blood mononuclear cells of 30 patients with RSV bronchopneumonia (1.5-24.0 months old group) were analyzed by flow cytometry analysis, and 15 normal infants (1.5-24.0 months old group) were enrolled as control group. The annual positive rate of RSV was 24.94%, 25.83%, 24.05%, 25.39% and 27.30% respectively from 2001 to 2005. It also found that the peak season for RSV infection was spring or winter (January to March or November to December). The positive rate of RSV was significantly higher in 1-12 months old group than that in > 12 months old group (chi2 = 97.320, P < 0.01), as well as the groups between 1-12 months old (chi2 = 7.804, P < 0.05, the highest positive rate was occurred at...Continue Reading

Related Concepts

Related Feeds

Cell Adhesion Molecules in the Brain

Cell adhesion molecules found on cell surface help cells bind with other cells or the extracellular matrix to maintain structure and function. Here is the latest research on their role in the brain.

Related Papers

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
Feng-Guo WanYunfang Ding
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]
Wei JiXuelan Zhang
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]
Wei JiYongdong Yan
© 2021 Meta ULC. All rights reserved