PMID: 9172043May 1, 1997Paper

Epidemiological typing of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates responsible for five outbreaks in a university hospital

The Journal of Hospital Infection
C BrangerN Lambert-Zechovsky

Abstract

Thirty-seven isolates of extended-spectrum beta-lactamase-producing (ESBL) Klebsiella pneumoniae implicated in five nosocomial outbreaks (I-V) on three distinct wards of our hospital were compared using capsular typing, biotyping, antibiotyping, enzyme electrophoresis typing and DNA macrorestriction analysis with Xba I resolved by pulsed-field gel electrophoresis. The isolates from each outbreak had common phenotypic and genotypic characteristics indicating that they were related epidemiologically. Isolates from outbreaks I (four patients) and V (13 patients), although they occurred in two different wards (neurology and surgery) and three years apart, produced the same ESBL with a pI of 7.8 (SHV-4) and were of serotype K25. The Xba I patterns were closely related. The isolates of outbreaks II (seven patients), III (four patients) and IV (seven patients), which occurred in a single surgical intensive care unit, produced an ESBL with a pI of 6.3 (TEM-3). Isolates from outbreaks III and IV, which occurred six months apart, were of serotype K68 and had similar Xba I patterns suggesting that the two outbreaks were due to a single strain which persisted endemically in the ward. The isolates from outbreak II were of serotype K62, and ...Continue Reading

References

Nov 19, 1977·British Medical Journal·M Casewell, I Phillips
Sep 1, 1991·Antimicrobial Agents and Chemotherapy·G A Jacoby, A A Medeiros
Nov 1, 1990·The Journal of Hospital Infection·B Ayling-Smith, T L Pitt
Nov 1, 1990·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·G ArletA Philippon
Feb 1, 1990·Antimicrobial Agents and Chemotherapy·A PetitJ Sirot
May 1, 1986·Applied and Environmental Microbiology·R K SelanderT S Whittam
Jun 1, 1989·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·P LegrandA Philippon
Sep 1, 1989·Infection·A PhilipponA Ben Hassen
Dec 1, 1988·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A BuréA Philippon
Jun 1, 1983·The Journal of Hospital Infection·G Reybrouck
Dec 1, 1993·The Journal of Hospital Infection·O ReishP Merlob
Jan 1, 1993·The Journal of Hospital Infection·L J GormanR G Masterton
Oct 1, 1996·Journal of Medical Microbiology·C BrangerN Lambert-Zechovsky

❮ Previous
Next ❯

Citations

Jun 11, 2011·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E RuppéB Fantin
Oct 15, 2005·Clinical Microbiology Reviews·David L Paterson, Robert A Bonomo
Feb 12, 2005·Emerging Infectious Diseases·Catherine BrangerErick Denamur
Jun 15, 2005·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·H Giamarellou
Aug 3, 2007·International Journal of Antimicrobial Agents·Miles Denton
Mar 7, 2008·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Anne KjerulfNiels Frimodt-Møller
Apr 8, 2010·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Debby Ben-DavidGalia Rahav
Jun 5, 2004·Clinics in Laboratory Medicine·Fernanda SilveiraDavid L Paterson
Nov 5, 2008·Journal of Industrial Microbiology & Biotechnology·Ginka I Frengova, Dora M Beshkova
Feb 21, 2009·The Journal of Nursing Education·Jenny E Vacek
May 2, 2003·Journal of Medical Microbiology·Thouraya Ben-HamoudaKamel Ben-Mahrez
Dec 25, 2007·Experimental Biology and Medicine·June Hsieh WuTing-Shu Wu
Jun 13, 2013·International Journal of Immunopathology and Pharmacology·P BernaschiL Putignani

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy & Infectious Diseases

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Allergy & Infectious Diseases (ASM)

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.