Epidemiology and antifungal susceptibility of bloodstream Candida isolates in Quebec: Report on 453 cases between 2003 and 2005.

The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Médicale
Guy St-GermainMichael Libman

Abstract

Between May 2003 and April 2005, a population-based surveillance of Candida bloodstream infections was conducted in Quebec. A total of 453 episodes of candidemia (464 yeast isolates) from 54 participating hospitals were studied. The annual incidence rate was three per 100,000 population. Global hospital mortality was 38%. The most common predisposing factors were the presence of an intravascular catheter (80%), use of antibacterial therapy (67%), stay in an intensive care unit (49%), use of parenteral nutrition (32%) and intra-abdominal surgery (31%). Fluconazole alone or in association with other antifungals was used for treatment in over 80% of cases. Candida albicans comprised 62% of isolates, followed by Candida glabrata (17%), Candida parapsilosis (9%), Candida tropicalis (5%), Candida lusitaniae (3%) and Candida krusei (3%). Of the 288 C albicans isolates, seven (2%) were resistant to flucytosine, one to fluconazole and none to itraconazole or voriconazole. Of the 75 non-C albicans species isolates with reduced susceptibility to fluconazole (minimum inhibitory concentration [MIC] 16 mug/mL or greater), none were susceptible to itraconazole (MIC 0.12 mg/L or lower), whereas 71 (95%) were susceptible to voriconazole (MIC 1 ...Continue Reading

Citations

Apr 27, 2012·Journal of Clinical Microbiology·Ana Alastruey-IzquierdoManuel Cuenca-Estrella
Mar 26, 2013·PloS One·Marcio NucciUNKNOWN Latin American Invasive Mycosis Network
Jan 6, 2018·The Journal of Antimicrobial Chemotherapy·Frederic LamothThierry Calandra
Feb 28, 2019·International Microbiology : the Official Journal of the Spanish Society for Microbiology·Guillermo QuindósElena Eraso
Feb 2, 2019·Chinese Medical Journal·Li-Juan ZhangJin-Xing Lu
Dec 21, 2012·Science Translational Medicine·Gordon D BrownTheodore C White
Mar 23, 2011·Expert Review of Anti-infective Therapy·Ozden Türel
Jun 20, 2013·Memórias do Instituto Oswaldo Cruz·Marcos Paulo WilleArnaldo Lopes Colombo
Apr 1, 2014·Medical Mycology Journal·Shinji KatsuragiJun Yoshimatsu
Jul 28, 2020·Canadian Journal of Microbiology·Linda C HorianopoulosAleeza C Gerstein
Oct 7, 2009·Expert Review of Anti-infective Therapy·Maria Teresa FeraAngelina De Sarro
Jul 1, 2011·Journal of Clinical Microbiology·Maiken Cavling ArendrupHelle Krogh Johansen
Jan 27, 2018·Journal of Fungi·Felix BongominDavid W Denning
Feb 17, 2018·Brazilian Journal of Biology = Revista Brasleira De Biologia·J N VieiraP S Nascente
May 12, 2018·Nature Reviews. Disease Primers·Peter G PappasBart Jan Kullberg
Sep 11, 2019·The Journal of Antimicrobial Chemotherapy·Jeff FullerUNKNOWN Canadian Antimicrobial Resistance Alliance (CARA) and CANWARD
Aug 17, 2010·Current Opinion in Critical Care·Maiken C Arendrup
Apr 12, 2011·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E BorghiG Morace
Oct 4, 2014·Clinical Microbiology Reviews·Kevin B Laupland, Deirdre L Church
Mar 4, 2011·Medical Mycology·Melanie W PoundRichard H Drew
Feb 6, 2017·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S F DufresneD C Sheppard
Aug 8, 2008·Journal of Clinical Microbiology·Donald C SheppardMichel Laverdiere

❮ Previous
Next ❯

Related Concepts

Related Feeds

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Related Papers

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Matthew E FalagasKonstantinos Z Vardakas
Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi
Yu-Ren ChengRen-Wen Tsay
Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
H RichetFrench Candidemia Study Group
© 2021 Meta ULC. All rights reserved