Epidemiology and characteristics of Guillain-Barré syndrome in the northwest of Iran

Annals of Saudi Medicine
Mohammad Ali AramiReza Khandaghi

Abstract

Little is known about the incidence of Guillain-Barré syndrome (GBS) in Iran. We determined the incidence and evaluated prognostic factors for GBS in a prospective, population-based study. We evaluated and followed all patients with a diagnosis of GBS admitted to three referral neurology centers in East Azerbaijan province over a 1-year period (2003). Clinical and electrophysiological characteristics of cases were reviewed and analyzed. A total of 76 patients were found, corresponding to a crude annual incidence rate of 2.11/100 000 population. Six patients (7.9%) died acutely within 21 days from the onset of the disease. Acute mortality was due to respiratory involvement, sepsis and acute autonomic system dysfunction. The persistence of disability after the acute phase was related to axonal involvement (OR=3.19, 95%CI, 1.65 to 6.16). There was a significant correlation between a history of diarrhea and a further need for mechanical ventilation (P<0.05). Mechanically ventilated patients had a low GBS disability score on discharge compared with patients not mechanically ventilated (P=0.05). The incidence rates of GBS in our province is similar to that in other countries. Acute mortality in GBS was mostly due to poor respiratory ...Continue Reading

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Citations

Jul 16, 2020·Irish Journal of Medical Science·Mirjana ArsenijevićStojan Peric
Mar 30, 2016·The American Journal of Tropical Medicine and Hygiene·Franciska S T SuryapranataRalph M H G Huits
Aug 2, 2016·Journal of the Peripheral Nervous System : JPNS·Gonzalo Rivera-LilloMauricio Hernández
Mar 1, 2018·The Medical Journal of Australia·Cameron GreenAshwin Subramaniam
Aug 18, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Mozaffar HosseininezhadZahra Gholipour Soleimani
Jun 20, 2018·Neurología : publicación oficial de la Sociedad Española de Neurología·J M AragonèsA Moreira

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