Epidemiology and pathogenesis of Kaposi's sarcoma-associated herpesvirus

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
C Boshoff, R A Weiss

Abstract

Kaposi's sarcoma (KS) occurs in Europe and the Mediterranean countries (classic KS) and Africa (endemic KS), immunosuppressed patients (iatrogenic or post-transplant KS) and those with acquired immune deficiency syndrome (AIDS), especially among those who acquired human immunodeficiency virus sexually (AIDS-KS). KS-associated herpesvirus (KSHV or HHV-8) is unusual among herpesviruses in having a restricted geographical distribution. Like KS, which it induces in immunosuppressed or elderly people, the virus is prevalent in Africa, in Mediterranean countries, among Jews and Arabs and certain Amerindians. Distinct KSHV genotypes occur in different parts of the world, but have not been identified as having a differential pathogenesis. KSHV is aetiologically linked to three distinct neoplasms: (i) KS, (ii) primary effusion lymphoma, and (iii) plasmablastic multicentric Castleman's disease. The histogenesis, clonality and pathology of the tumours are described, together with the epidemiology and possible modes of transmission of the virus.

References

Nov 1, 1979·The American Journal of Medicine·A R HarwoodR A Giammarco
May 15, 1975·International Journal of Cancer. Journal International Du Cancer·G GiraldoA Puissant
May 1, 1976·British Journal of Cancer·C L OlwenyJ L Ziegler
Feb 29, 1992·Lancet·Y Q HuangA E Friedman-Kien
Oct 1, 1992·AIDS Research and Human Retroviruses·M StürzlW K Roth
Dec 1, 1992·British Journal of Cancer·A E GrulichA J Swerdlow
Jun 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·S A MilesT Kishimoto
Dec 24, 1990·Clinica Chimica Acta; International Journal of Clinical Chemistry·S E DaviesR A Chalmers
Jan 1, 1991·Annual Review of Biochemistry·Y N Vaishnav, F Wong-Staal
Feb 1, 1989·Journal of the Royal Army Medical Corps·B J Heap, J D Mumford
Feb 1, 1988·The American Journal of Medicine·W QunibiS Taher
Dec 1, 1972·Journal of the National Cancer Institute·G GiraldoF Haguenau
Aug 1, 1972·Cancer·J J D'Oliveira, F O Torres
Jan 1, 1984·The Journal of Allergy and Clinical Immunology·P S CreticosN F Adkinson
Nov 18, 1995·Lancet·J C Noel
May 23, 1995·Proceedings of the National Academy of Sciences of the United States of America·A AlbiniB Ensoli
Sep 27, 1995·International Journal of Cancer. Journal International Du Cancer·M T BassettD M Parkin
Jul 1, 1995·Nature Medicine·M SchallingP Biberfeld
Jul 5, 1995·Journal of the National Cancer Institute·M GeddesR Zanetti
May 4, 1995·The New England Journal of Medicine·E CesarmanD M Knowles
May 6, 1995·Lancet·C LebbéF Calvo
Oct 28, 1994·Science·S W BarnettJ A Levy
Apr 22, 1993·International Journal of Cancer. Journal International Du Cancer·H R WabingaJ W Mugerwa
Jan 3, 1996·International Journal of Cancer. Journal International Du Cancer·F M BuonaguroG Giraldo
Jan 17, 1996·International Journal of Cancer. Journal International Du Cancer·J L Ziegler, E Katongole-Mbidde

❮ Previous
Next ❯

Citations

Nov 10, 2007·Cancer Causes & Control : CCC·Aruna Alahari DhirK A Dinshaw
Dec 14, 2002·Trends in Cell Biology·Laurent Coscoy, Don Ganem
Dec 18, 2007·Cell Death and Differentiation·A M Flanagan, A Letai
Apr 25, 2003·The New England Journal of Medicine·Sylvie EuvrardAlain Claudy
Sep 30, 2010·The Journal of Experimental Medicine·Minji ByunJean-Laurent Casanova
Jul 31, 2013·The Journal of Experimental Medicine·Minji ByunJean-Laurent Casanova
Aug 19, 2007·The Journal of Infectious Diseases·Vanda A U F de SouzaClaudio S Pannuti
Jul 20, 2011·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Shuhei Sakakibara, Giovanna Tosato
Jul 12, 2007·Journal of the National Cancer Institute·Renan DuprezAntoine Gessain
May 17, 2014·PLoS Neglected Tropical Diseases·Edouard BetsemAntoine Gessain
Nov 20, 2002·Biological Chemistry·Davide BisacchiUlrich Pfeffer
Feb 17, 2010·Pediatrics·Gürses SahinSabine Plancoulaine
Apr 9, 2008·Emerging Infectious Diseases·Sam M MbulaiteyeJames J Goedert
Apr 1, 2009·Emerging Infectious Diseases·Maria C NascimentoPhilippe Mayaud
May 29, 2010·Emerging Infectious Diseases·Vanda A U F SouzaClaudio S Pannuti
Sep 20, 2006·Proceedings of the National Academy of Sciences of the United States of America·Meir ShamayS Diane Hayward
Oct 3, 2007·Proceedings of the National Academy of Sciences of the United States of America·Ke LanErle S Robertson
Aug 20, 2003·Proceedings of the National Academy of Sciences of the United States of America·Richard G JennerPaul Kellam
Apr 8, 2006·European Journal of Pediatrics·Capucine PicardMohamed Bejaoui
Jul 16, 2011·American Journal of Clinical Pathology·Eric D HsiAhmet Dogan
Sep 24, 2015·Autophagy·Marisa GranatoMara Cirone
Jun 21, 2002·The Journal of General Virology·Rachelle D CookStephen R Porter
Mar 5, 2004·Biochimica Et Biophysica Acta·Brian M PolsterJ Marie Hardwick
Jul 11, 2003·Hematology/oncology Clinics of North America·Sam M MbulaiteyeCharles S Rabkin
Dec 2, 2009·International Journal of STD & AIDS·K McCarthyW D F Venter
Jun 24, 2017·Journal of Investigative Medicine High Impact Case Reports·Vivek KumarJonathan Harris
Apr 8, 2003·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Sam M MbulaiteyeEric A Engels

❮ Previous
Next ❯

Related Concepts

Related Feeds

Castleman Disease

Castleman disease is a rare disorder that involves an overgrowth of cells in the lymph nodes. Unicentric Castleman disease affects one lymph node, usually in the chest or abdomen. Multicentric Castleman disease affects multiple lymph nodes, commonly located in the neck, collarbone, underarm and groin areas. Discover the latest research on Castleman disease here.

AIDS Malignancies (ASM)

HIV infection increases the risk of non-communicable diseases common in the aged, including cardiovascular disease, neurocognitive decline, non-aids malignancies, osteoporosis, and frailty. Discover the latest research in AIDS malignancies.

HIV/AIDS-Related Malignancies

HIV/AIDS infection increases the risk of non-communicable diseases common in the aged including HIV/AIDS-related malignancies. Discover the latest research in HIV/AIDS-related malignancies.