Epidemiology and prevention of pancreatic cancer

Japanese Journal of Clinical Oncology
A B Lowenfels, P Maisonneuve

Abstract

Pancreatic cancer is an uncommon tumor, but because the mortality rate approaches 100%, this form of cancer has now become a common cause of cancer mortality. In the United States it is the fourth most frequent cause of cancer mortality; in Japan it ranks as the fifth commonest cause of death from cancer. Smoking is the major known risk factor for pancreatic cancer, accounting for approximately 25-30% of all cases. Some of the time-dependent changes in the frequency of pancreatic cancer can be explained by smoking trends. Aggressive public health measures to control smoking would substantially reduce the burden of pancreatic cancer. Dietary factors are less important for pancreatic cancer than for other digestive tract tumors, but consumption of a diet with adequate quantities of fruits and vegetables, plus control of calories either by dietary measures or by exercise will help to prevent this lethal tumor. There are more than a dozen inherited germline mutations that increase the risk of pancreatic cancer. Of these, hereditary pancreatitis confers the greatest risk, while BRCA2 mutations are the commonest inherited disorder. In addition to germline defects, there are several common polymorphisms in genes that control detoxific...Continue Reading

Citations

May 24, 2007·Cancer Chemotherapy and Pharmacology·Takuji OkusakaHiroshi Saito
Apr 7, 2006·Virchows Archiv : an International Journal of Pathology·Heike ImmervollAnders Molven
May 16, 2006·Apoptosis : an International Journal on Programmed Cell Death·Marco RosettiWainer Zoli
Jan 16, 2007·Cancer Causes & Control : CCC·Ute NöthlingsLaurence N Kolonel
Jan 16, 2009·Cancer Causes & Control : CCC·Sabine RohrmannH Bas Bueno-de-Mesquita
Feb 26, 2010·Cancer Causes & Control : CCC·Jing ZhouKangmin Zhu
Apr 23, 2008·Cancer Metastasis Reviews·Alexios StrimpakosKostas N Syrigos
May 22, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Theresa P YeoCharles J Yeo
Apr 2, 2005·Current Gastroenterology Reports·Albert B LowenfelsPatrick Maisonneuve
Oct 1, 2009·Palliative & Supportive Care·Kerri PetrinRobin Bennett
Jan 10, 2012·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Yeon Tae ChungGuang-Yu Yang
May 10, 2007·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J ZhangUNKNOWN SEER Cancer Registries
Sep 9, 2006·Journal of Gastroenterology and Hepatology·Thilo WelschMarkus W Büchler
Sep 21, 2011·Journal of Gastroenterology and Hepatology·Kuan-Fu LiaoWen-Chi Chen
Dec 17, 2011·Cancer Research·Ernest T LamGregory J Tranah
Feb 10, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Noel T MuellerMark A Pereira
Jul 27, 2007·International Journal of Health Geographics·Setsuko KinoshitaMasafumi Okada
Feb 23, 2013·International Journal of Molecular Sciences·Johannes LemkeMarko Kornmann
Jan 22, 2011·Gut and Liver·Alexios S StrimpakosMuhammad Wasif Saif
Sep 15, 2009·Environmental Health Perspectives·Brenda EskenaziDarwin Stapleton
Jun 20, 2013·Gastroenterology Research and Practice·Lixin YangJiaming Qian
Jul 8, 2010·World Journal of Surgery·Mehdi OuaissiUNKNOWN Multidisciplary HPB Group of Center of Cancer
Nov 6, 2009·Cutaneous and Ocular Toxicology·Ivan BustilloMuhammad Wasif Saif
Oct 29, 2010·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Seema GuptaMansoor M Ahmed
Nov 13, 2009·Journal de chirurgie·T BègeC Brunet
Sep 24, 2009·Gastroentérologie Clinique Et Biologique·A-C LefebvreD Arsene
Aug 18, 2009·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Dorthe JohansenJonas Manjer
Jun 30, 2009·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Randall E BrandMichelle A Anderson
Nov 3, 2015·Cancer Epidemiology·Daroh LimInmyung Song
May 22, 2007·The Journal of Surgical Research·Shi-He LiuF Charles Brunicardi
Feb 27, 2007·Cancer Letters·F H Schmitz-WinnenthalK Z'graggen
Dec 13, 2006·The Journal of Surgical Research·Shihe LiuF Charles Brunicardi
Feb 10, 2010·International Journal of Cancer. Journal International Du Cancer·Sara H OlsonRobert C Kurtz

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