Epidemiology and prognostic factors in severe sepsis/septic shock. Evolution over six years

Medicina intensiva
I AzkárateR Salaberria

Abstract

To determine the clinical characteristics and prognostic factors of patients with severe sepsis/septic shock admitted to the Intensive Care Unit of Donostia University Hospital (Guipuzcoa, Spain). A prospective, observational study was carried out during a consecutive 6-year period (1st February 2008-31st December 2013). The Intensive Care Unit of Donostia University Hospital, the only third level hospital in the province of Guipuzcoa, with a recruitment population of 700,000 inhabitants. Number of patients with severe sepsis/septic shock has progressively increased over the last years to reach 1,136 patients, yet significant changes in age, sex, Acute Physiology and Chronic Health Evaluation II, procalcitonin and lactate values could not be observed. In the last years, admission rate from Emergency Department has increased in comparison to admissions from hospitalization ward, with a higher incidence of urological sepsis. Hemodynamic and renal dysfunctions have been the most prevalent disorders, respiratory involvement and thrombocytopenia have gone down while coagulopathy has increased significantly. Mortality has decreased significantly. We have performed a multivariate analysis of the early prognostic factors. Type, origin,...Continue Reading

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Citations

Apr 17, 2016·Medicina intensiva·E J García-LamberechtsJ González Del Castillo
May 21, 2016·Medicina intensiva·I AzkárateR Sebastián
Mar 1, 2010·Reumatología clinica·Virginia Villaverde García, Alejandro Balsa Criado
Oct 25, 2016·Medicina intensiva·L García-LópezUNKNOWN Grupo de Trabajo Multidisciplinar en Código Sepsis del Hospital Clínico Universitario de Valladolid
Feb 9, 2016·The Journal of Craniofacial Surgery·Jin Yong ShinKyung-Moo Yang
Aug 27, 2015·Critical Care : the Official Journal of the Critical Care Forum·José Garnacho-MonteroJosé María López-Sánchez
Jan 12, 2021·The Journal of International Medical Research·Huang Hongwei
Oct 16, 2020·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Xinghui WuHuasheng Tong
Aug 7, 2021·Clinics in Chest Medicine·Tasnim I LatHeath D White

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