Epidemiology and prognostic factors of critically ill patients treated with hemodiafiltration

Journal of Critical Care
Stéphane SoubrierBenoit Guery

Abstract

The objective of this study is to study the epidemiology, outcome, and prognostic factors of critically ill patients treated with continuous venovenous hemodiafiltration (CVVHDF). Observational cohort was done in a French 16-bed intensive care unit (ICU) from a university-affiliated urban hospital. All patients requiring, in the opinion of the treating physician, the initiation of CVVHDF were included in the study. One hundred ninety-seven patients with acute renal failure (ARF) treated with CVVHDF were studied. The incidence of ARF treated with CVVHDF was 5.9% in the ICU with a mortality rate of 71.6%. A multivariate analysis identified 3 independent factors associated with fatal outcome: mechanical ventilation, sepsis, and septic shock requiring vasoactive drug. In contrast, 2 independent factors predicted a favorable outcome: nonoliguric ARF and serum creatinine concentration higher than 34 mg/L at CVVHDF initiation. A flowchart determined by the chi2 Automatic Interaction and Detection statistical method allowed for the identification of patients' subgroups with different mortality rates ranging from 25% to 100%. In our series, ARF treated with CVVHDF was associated with a high overall ICU mortality rate (71.6%). However, o...Continue Reading

References

Jan 1, 1991·Intensive Care Medicine·J H SchaeferA Distler
Dec 1, 1985·Annals of Surgery·W A KnausJ E Zimmerman
Jul 13, 1974·Lancet·G Teasdale, B Jennett
Jul 24, 1995·Archives of Internal Medicine·G M ChertowJ M Lazarus
Jul 21, 2000·American Journal of Respiratory and Critical Care Medicine·L ColeJ H Reeves
Sep 16, 2000·Intensive Care Medicine·A de MendonçaF Cantraine
Feb 1, 2002·The New England Journal of Medicine·Helmut SchifflRainald Fischer

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Citations

Mar 12, 2013·Journal of Anesthesia·Takeshi UmegakiYuichi Imanaka
Feb 25, 2009·Critical Care Medicine·Anne-Cornélie J M de Pont
Feb 15, 2012·Seminars in Dialysis·Bernd StegmayrRasheed A Balogun
Mar 21, 2012·Seminars in Dialysis·Bernd StegmayrRasheed A Balogun
May 22, 2008·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Bernd Stegmayr
Aug 7, 2007·Best Practice & Research. Clinical Rheumatology·Daniel Aletaha, Josef S Smolen
Apr 10, 2014·International Journal of Cardiology·Chiara LazzeriSerafina Valente
Nov 2, 2006·Current Opinion in Critical Care·Sean M Bagshaw
Nov 14, 2008·Current Opinion in Critical Care·Etienne MacedoRavindra L Mehta
Mar 22, 2014·Clinical Journal of the American Society of Nephrology : CJASN·F Perry WilsonHarold I Feldman
Jul 9, 2021·Kidney Research and Clinical Practice·Kristianne Rachel P Medina-LiabresSejoong Kim

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