Epidemiology and Risk Factors of Nonalcoholic Fatty Liver Disease Among Patients with Inflammatory Bowel Disease

Inflammatory Bowel Diseases
Kerri GlassnerBincy P Abraham

Abstract

Nonalcoholic fatty liver disease (NAFLD) has been increasingly identified in patients with inflammatory bowel disease (IBD). We aimed to determine risk factors of NAFLD in patients with IBD. We examined 3 groups of patients: IBD + NAFLD, IBD only, and NAFLD only. Data on demographics, body mass index, duration of IBD, type of medication use, laboratory data, and metabolic risk factors were collected. A total of 168 patients between the ages 19 and 82 were evaluated, 56 patients in each group. Patients with IBD + NAFLD were significantly older than IBD only patients 45.0 (±14.1) versus 35.0 (±13), P = 0.007, and their mean body mass index was higher 30.4 (±10.2) versus 25.6 (±6.4); P = 0.002. IBD + NAFLD patients in comparison with IBD only patients had significantly longer duration of IBD (20 [±12.2] versus 10 [±7.7], P = 0.004), had an increased risk of diabetes (16% versus 2%, P = 0.01), and obesity (40% versus 20%, P = 0.02). There were no differences in the mean age or the mean body mass index (32.6 versus 30.4, P = 0.07) between patients with IBD + NAFLD and NAFLD only. More patients were obese in the NAFLD only group compared with the IBD + NAFLD group (59% versus 40%, P = 0.03), had hypertension (55% versus 33%, P = 0.02...Continue Reading

References

May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
May 11, 2002·The American Journal of Gastroenterology·S P DourakisP Kaliopi
Feb 27, 2003·Journal of Internal Medicine·M CandelliA Gasbarrini
Apr 25, 2007·Inflammatory Bowel Diseases·Javier P GisbertJosé Maté
Mar 1, 2008·Journal of the American College of Surgeons·Clifford S ChoMichael I D'Angelica
Jul 16, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·David van der PoortenJacob George
Mar 17, 2010·Best Practice & Research. Clinical Gastroenterology·Gerhard Rogler
May 28, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Ruben HernaezJeanne M Clark
Sep 14, 2013·Digestive Diseases·V WieserH Tilg
Sep 18, 2013·Nature Reviews. Gastroenterology & Hepatology·Rohit Loomba, Arun J Sanyal
Oct 1, 2013·Journal of Autoimmunity·Jorge Henao-MejiaRichard A Flavell
Nov 22, 2013·World Journal of Gastroenterology : WJG·María Rojas-FeriaManuel Romero-Gómez
Aug 1, 2015·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Aijaz AhmedStephen A Harrison
Mar 10, 2016·The American Journal of Gastroenterology·Toufic A KabbaniDavid G Binion

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Citations

Dec 29, 2017·Obesity Surgery·Stephanie AelfersFrits J Berends
Apr 27, 2018·European Journal of Gastroenterology & Hepatology·Kamolyut LapumnuaypolWisit Cheungpasitporn
Mar 7, 2019·European Journal of Gastroenterology & Hepatology·Cátia ArieiraJosé Cotter
Feb 12, 2020·European Journal of Gastroenterology & Hepatology·Katerina KaraivazoglouChristos Triantos
Apr 25, 2018·Inflammatory Bowel Diseases·Mariabeatrice PrincipiAlfredo Di Leo
Feb 6, 2019·Nutrients·Rocco SpagnuoloArturo Pujia
Jul 16, 2020·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Rosellina Margherita MancinaRocco Spagnuolo
Dec 22, 2020·Journal of Pediatric Gastroenterology and Nutrition·Mallory E CohenCharles M Samson
Aug 11, 2021·Inflammatory Bowel Diseases·Shaya NoorianBerkeley N Limketkai
Jan 1, 2022·Journal of Crohn's & Colitis·Apostolis PapaefthymiouStergios A Polyzos

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