Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study

Matthew J CummingsMax R O'Donnell


Over 40 000 patients with COVID-19 have been hospitalised in New York City (NY, USA) as of April 28, 2020. Data on the epidemiology, clinical course, and outcomes of critically ill patients with COVID-19 in this setting are needed. This prospective observational cohort study took place at two NewYork-Presbyterian hospitals affiliated with Columbia University Irving Medical Center in northern Manhattan. We prospectively identified adult patients (aged ≥18 years) admitted to both hospitals from March 2 to April 1, 2020, who were diagnosed with laboratory-confirmed COVID-19 and were critically ill with acute hypoxaemic respiratory failure, and collected clinical, biomarker, and treatment data. The primary outcome was the rate of in-hospital death. Secondary outcomes included frequency and duration of invasive mechanical ventilation, frequency of vasopressor use and renal replacement therapy, and time to in-hospital clinical deterioration following admission. The relation between clinical risk factors, biomarkers, and in-hospital mortality was modelled using Cox proportional hazards regression. Follow-up time was right-censored on April 28, 2020 so that each patient had at least 28 days of observation. Between March 2 and April 1, ...Continue Reading

Associated Clinical Trials

Mar 16, 2021·Carlos Augusto Celemín Florez, MD.


Jul 1, 2020·JAMA Internal Medicine·Pratik SinhaCarolyn S Calfee
Jul 3, 2020·Cardiology in the Young·Michael A FremedThomas J Starc
Jun 20, 2020·Pediatric Pulmonology·Jose A Castro-Rodriguez, Erick Forno
Jul 9, 2020·Journal of Gerontological Social Work·Susanny J Beltran, Vivian J Miller
Jun 20, 2020·Journal of Medical Virology·Ravindra Kumar GargAnkit Gupta
Jul 21, 2020·Arteriosclerosis, Thrombosis, and Vascular Biology·Bernard S KadoshStuart D Katz
Jul 21, 2020·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Alan T ChiemYiju Teresa Liu
Jul 4, 2020·The American Journal of Tropical Medicine and Hygiene·Laura McArthurCharles A Narh
Jul 24, 2020·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Dimitrios MorisAndrew S Barbas
Jun 17, 2020·Anesthesia and Analgesia·Dusan Hanidziar, Edward A Bittner
Jul 8, 2020·Antimicrobial Agents and Chemotherapy·Miguel Angel Martinez
Aug 21, 2020·Clinical Trials : Journal of the Society for Clinical Trials·Kay See Tan
Aug 22, 2020·JAMA : the Journal of the American Medical Association·Christoph D SpinnerUNKNOWN GS-US-540-5774 Investigators
Aug 29, 2020·Daru : Journal of Faculty of Pharmacy, Tehran University of Medical Sciences·Hamid RahmaniMir Saeed Yekaninejad
Sep 1, 2020·Acta Diabetologica·Giuseppe PuglieseEmanuela Orsi
Sep 4, 2020·The Oncologist·Evan C ChenJean M Connors
Sep 16, 2020·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Tu-Hsuan ChangLuan-Yin Chang
Jul 29, 2020·Clinical Medicine : Journal of the Royal College of Physicians of London·Luke DancyAjay M Shah
Sep 29, 2020·Journal of Cardiac Surgery·Subhasis ChatterjeeJoseph S Coselli
Jul 1, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Reed MaglebyMichael J Satlin
Oct 2, 2020·Infection·Carolin E M JakobJörg Janne Vehreschild
Oct 2, 2020·Infectious Diseases·Halil YildizDiego Castanares-Zapatero
Jul 31, 2020·Der Internist·M Pfeifer, O W Hamer
Aug 10, 2020·ANZ Journal of Surgery·Joshua G KovoorGuy J Maddern
Aug 23, 2020·International Journal of Molecular Sciences·Grégorie LebeauPhilippe Gasque
Sep 5, 2020·BMJ Evidence-based Medicine·Jamie Hartmann-BoycePaddy Dennison
Aug 19, 2020·Critical Care : the Official Journal of the Critical Care Forum·Darryl AbramsDaniel Brodie
May 29, 2020·BMJ : British Medical Journal·George L AnesiM Kit Delgado
Aug 18, 2020·Clinical Journal of the American Society of Nephrology : CJASN·Daniil Shimonov, Vesh Srivatana
Jul 15, 2020·Acta Physiologica·Jan-Hendrik B Hardenberg, Friedrich C Luft
Aug 28, 2020·Frontiers in Medicine·Santosh Dhakal, Surendra Karki
Aug 5, 2020·The European Respiratory Journal·Lieuwe D J BosRobert P Dickson
Sep 24, 2020·Gefässchirurgie : Zeitschrift für vaskuläre und endovaskuläre Chirurgie : Organ der Deutschen und der Österreichischen Gesellschaft für Gefässchirurgie unter Mitarbeit der Schweizerischen Gesellschaft für Gefässchirurgie·B NeetzM M Müller

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