Epidemiology of Acute Respiratory Distress Syndrome Following Hematopoietic Stem Cell Transplantation

Critical Care Medicine
Hemang YadavDaryl J Kor

Abstract

Pulmonary complications are common following hematopoietic stem cell transplantation. Numerous idiopathic post-transplantation pulmonary syndromes have been described. Patients at the severe end of this spectrum may present with hypoxemic respiratory failure and pulmonary infiltrates, meeting criteria for acute respiratory distress syndrome. The incidence and outcomes of acute respiratory distress syndrome in this setting are poorly characterized. Retrospective cohort study. Mayo Clinic, Rochester, MN. Patients undergoing autologous and allogeneic hematopoietic stem cell transplantation between January 1, 2005, and December 31, 2012. None. Patients were screened for acute respiratory distress syndrome development within 1 year of hematopoietic stem cell transplantation. Acute respiratory distress syndrome adjudication was performed in accordance with the 2012 Berlin criteria. In total, 133 cases of acute respiratory distress syndrome developed in 2,635 patients undergoing hematopoietic stem cell transplantation (5.0%). Acute respiratory distress syndrome developed in 75 patients (15.6%) undergoing allogeneic hematopoietic stem cell transplantation and 58 patients (2.7%) undergoing autologous hematopoietic stem cell transplantat...Continue Reading

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Citations

Jan 4, 2017·American Journal of Respiratory and Critical Care Medicine·Hemang YadavOgnjen Gajic
Apr 15, 2017·Critical Care Medicine·Philipp WohlfarthUNKNOWN Caring for Critically Ill Immunocompromised Patients Multinational Network (NINE-I)
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Dec 6, 2018·Current Opinion in Critical Care·Bruno L Ferreyro, Laveena Munshi
May 22, 2019·The European Respiratory Journal·Philippe R BauerUNKNOWN Efraim investigators and the Nine-I study group
Jul 11, 2019·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Mohammad HamidiSangeeta Mehta
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Oct 30, 2018·World Journal of Critical Care Medicine·Patrick M WieruszewskiHemang Yadav
Apr 23, 2020·British Journal of Haematology·Gerhard C Hildebrandt, Nelson Chao
Mar 9, 2019·Wiener klinische Wochenschrift·Philipp Wohlfarth
Feb 11, 2021·Medizinische Klinik, Intensivmedizin und Notfallmedizin·S-S StecherA Fraccaroli
Dec 11, 2020·Annals of the American Thoracic Society·Patrick M WieruszewskiHemang Yadav

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Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

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