Epidemiology of Adult Soft-Tissue Sarcomas in Germany

Sarcoma
Catherine W SaltusJames A Kaye

Abstract

We conducted a retrospective cohort study using data compiled from the regional German cancer registries by the Centre for Cancer Registry Data (ZfKD) at the Robert Koch Institut (RKI) to describe the epidemiology of adult soft-tissue sarcomas (STS) in Germany in 2003-2012, focusing on advanced STS. We identified 33,803 incident adult cases of STS (other than the Kaposi sarcoma and gastrointestinal stromal tumors). The incidence of STS was 6.05 (95% confidence interval (CI), 5.82-6.29) per 100,000 in 2012 (4,079 cases). During 2003-2012, the most common histologic categories were leiomyosarcoma (19%), liposarcoma (16%), and STS not otherwise specified (14%). The overall STS-specific mortality rate in 2012 was 2.31 (95% CI, 2.06-2.57) per 100,000, and the median overall survival from initial diagnosis was 5.83 (95% CI, 5.50-6.08) years. Using STS mortality rates as a proxy for incidence of advanced STS in Germany and applying the age- and sex-specific rates to the corresponding German population, we estimated that 1,581 incident adult advanced STS cases occurred in Germany in 2012. Our findings contribute to a refined understanding of the population burden of STS in Germany, including the number of patients with advanced STS who...Continue Reading

References

May 22, 2007·The Journal of Surgical Research·Juan C GutierrezLeonidas G Koniaris
Oct 22, 2011·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·U WolfB-M Kurth
Oct 29, 2011·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Gemma GattaUNKNOWN RARECARE working group
Oct 20, 2012·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C A StillerUNKNOWN RARECARE Working Group

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Citations

May 16, 2020·Radiation Oncology·Gustavo R SarriaFrank A Giordano
Apr 23, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Natalia Magdalena ChrzanowskaMarzena Anna Lewandowska
Jun 18, 2020·Surgical Case Reports·Samra GafarliBarbara Stange
Jul 29, 2021·Molecular Cancer Therapeutics·Finith JerniganMarla Weetall
Apr 23, 2021·Oncology Research and Treatment·Martin EichlerMarkus K Schuler

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Software Mentioned

CI5
RARECARE
EUROCARE
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