Epidemiology of chronic hepatitis C in Germany--an analysis of 10,326 patients in hepatitis centres and outpatient units

Zeitschrift für Gastroenterologie
D HüppeC Niederau

Abstract

Little is known about the epidemiology of chronic hepatitis C (CHC) in Germany and especially about the importance of transmission, duration of infection, genotypes, symptoms and quality of life of the patients. The current study prospectively evaluates epidemiological and clinical data of patients infected with the hepatitis C virus (HCV). Using online data entry, various characteristics of 10,326 untreated patients with CHC were documented from March 2003 until May 2006 in 352 centres all over Germany. Mean age of patients was 43.4 years. Patients infected by i.v. drug abuse were considerably younger (36.5 years) than the remaining patients (49.2 years). As indicated by their native language, 64.4% of the patients came from Germany and 19.2% from Russia. 61.7% were infected with genotype 1 and 34.9% with genotype 2 or 3. 45.5% of the patients had been infected by i.v. drug abuse. In at least 5.4% of the patients liver cirrhosis had been proved by biopsy. 63.5% of the patients felt an impairment of quality of life caused by CHC. In many patients infected with hepatitis C socio-economic issues are existent. This is reflected, i.e., in very high rates of unemployment in special subpopulations. Coinfections with hepatitis B and H...Continue Reading

Citations

Apr 12, 2012·World Journal of Gastroenterology : WJG·Claus NiederauStefan Mauss
Aug 26, 2014·World Journal of Gastroenterology : WJG·Claudia RoederStefan Lueth
Dec 3, 2014·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Francesco Negro
Jun 5, 2016·MMW Fortschritte der Medizin·Reinhart Zachoval, Maria-Christina Jung
May 4, 2017·BMJ Open Gastroenterology·Urbano SbarigiaChristian Krauth
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Aug 22, 2014·European Journal of Gastroenterology & Hepatology·Jona T StahmeyerChristian Krauth
Dec 4, 2019·BMC Infectious Diseases·Christian KrauthJona Theodor Stahmeyer
Oct 6, 2020·Frontiers in Public Health·Ida SperleSandra Dudareva

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