Epidemiology of diabetes among South Asians in the United States: lessons from the MASALA study.

Annals of the New York Academy of Sciences
Unjali P Gujral, Alka M Kanaya

Abstract

South Asian individuals in the United States are at an increased risk of type 2 diabetes (T2DM); however, the mechanisms behind this are not well understood. The Mediators of Atherosclerosis in South Asians Living in America (MASALA) study is the only longitudinal cohort of South Asians in the United States and provides key insights as to the epidemiology of T2DM in South Asians. Evidence from the MASALA study suggests that South Asians experience a disproportionately high burden of prevalent and incident T2DM compared with members of other race/ethnic groups. Higher insulin resistance in South Asians, even with low body mass index (BMI), more impairment in insulin secretion, and greater deposition of ectopic fat likely play a role in T2DM etiology. Furthermore, South Asian migrants to the United States experience a range of factors related to acculturation, social networks, and religious beliefs, which may impact physical activity and dietary practices. Interventions to prevent T2DM in South Asians should include a focus on cultural factors related to health and should consider the complete mechanistic pathway and the relative contributions of insulin resistance, β cell dysfunction, and ectopic fat deposition on T2DM developme...Continue Reading

References

Jul 18, 1991·The New England Journal of Medicine·S P HelmrichR S Paffenbarger
Sep 24, 1999·Journal of Women's Health & Gender-based Medicine·B E AinsworthL M Stolarczyk
Oct 3, 1999·Annals of Internal Medicine·N C NetzerK P Strohl
Oct 25, 2002·American Journal of Epidemiology·Diane E BildRussell P Tracy
Jun 27, 2003·Diabetologia·T NakagamiUNKNOWN DECODE-DECODA Study Group
Aug 26, 2003·The American Journal of Clinical Nutrition·David J A JenkinsJames W Anderson
Sep 10, 2003·Journal of the American Dietetic Association·Linda E KelemenUNKNOWN SHARE Investigators
Mar 31, 2004·Diabetic Medicine : a Journal of the British Diabetic Association·W B ChanJ C N Chan
Dec 24, 2004·Diabetes·David E LaaksonenUNKNOWN Finnish diabetes prevention study
Jan 12, 2005·The Diabetes Educator·Lonnie K WenMichael L Parchman
Sep 30, 2005·American Journal of Respiratory and Critical Care Medicine·Kevin J ReichmuthTerry Young
Jul 11, 2006·The Journal of Clinical Investigation·Masato Kasuga
Aug 30, 2007·Diabetic Medicine : a Journal of the British Diabetic Association·V A DiazA Majeed
Feb 7, 2008·Chest·Esra TasaliEve Van Cauter
Jun 11, 2008·American Journal of Preventive Medicine·Fuzhong LiJane M Moore
Jun 19, 2008·Reviews on Environmental Health·David O Carpenter
Oct 10, 2008·The British Journal of Nutrition·Anoop MisraSwati Bhardwaj
Jun 3, 2009·Nature Reviews. Endocrinology·Peter D GluckmanAlan S Beedle
Jul 10, 2009·Psychological Bulletin·Elizabeth A Pascoe, Laura Smart Richman
Jul 18, 2009·American Journal of Public Health·Reena Oza-Frank, K M Venkat Narayan
Aug 19, 2009·Journal of Immigrant and Minority Health·Reena Oza-FrankK M Venkat Narayan
Oct 31, 2009·Diabetes·James R BainChristopher B Newgard
Dec 5, 2009·The American Journal of Medicine·Nader BotrosHenry Klar Yaggi
Jun 8, 2010·Journal of Epidemiology and Community Health·Emily D WilliamsMark Hamer
Jan 29, 2011·Diabetes Care·Andrea BankoskiAnnemarie Koster
Mar 23, 2011·Nature Medicine·Thomas J WangRobert E Gerszten
Jun 18, 2011·Diabetes Care·Maria ChiuJack V Tu
Jul 1, 1997·Journal of Health Psychology·D R WilliamsN B Anderson
Jan 16, 2013·Annals of the New York Academy of Sciences·Unjali P GujralV Mohan
Jul 23, 2013·American Journal of Preventive Medicine·Jana A HirschAna V Diez Roux

❮ Previous
Next ❯

Citations

Jul 31, 2021·American Journal of Preventive Cardiology·Harold E BaysPeter P Toth

❮ Previous
Next ❯

Related Concepts

Related Feeds

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.

Related Papers

European Journal of Endocrinology
Leontine E H BakkerIngrid M Jazet
Journal of Diabetes and Its Complications
Anoop MisraR Pradeepa
Advance for Nurse Practitioners
Khalid Hussain
CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne
Arun K Garg, Pamela Verma
© 2021 Meta ULC. All rights reserved