PMID: 15232184Jul 3, 2004Paper

Epidemiology of diseases caused by Streptococcus pyogenes in Serbia during a nine-year period (1991-1999)

The Indian Journal of Medical Research
L RaninV Mijac

Abstract

Streptococcus pyogenes (group A Streptococcus - GAS) is an important human pathogen which causes a variety of diseases, including tonsillopharyngitis, scarlet fever and rheumatic fever. It is important to understand the changes in epidemiology of the diseases caused by the pathogen for improved control of such infections. Hence, the aim of the present study was to carry out an epidemiological analysis of GAS infections in Serbia in a 9-yr period (1991-1999) and evaluation of susceptibility of GAS isolates obtained during the same period to penicillin and erythromycin. Occurrence of tonsillopharyngitis, scarlatina and rheumatic fever was analyzed and GAS carrier status in healthy children was examined over a 9-yr period from 1991 to 1999. Susceptibility to penicillin and erythromycin was determined for 1657 GAS isolates obtained from patients diagnosed with pharyngitis or scarlet fever and 512 isolates from healthy carriers. M-type antigen was also determined in these isolates. The average incidences of tonsillopharyngitis and scarlet fever were 76.2 and 30.8 per cent respectively. A total of 166 cases of rheumatic fever were registered. Per cent of carriers varied from 5.5 to 11.4 per cent over the study period. Predominating M...Continue Reading

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