Epidemiology of infective endocarditis in transcatheter aortic valve replacement: systemic review and meta-analysis.

Journal of Cardiovascular Medicine
Narut PrasitlumkumJonathan Dworkin

Abstract

Infective endocarditis following transcatheter aortic valve replacement (TAVR) is an emerging problem, with a high rate of morbidity and mortality. However, little is known about the burden of disease, and data on infective endocarditis incidence are scarce. This study aimed to evaluate the incidence of infective endocarditis in TAVR by performing a systematic review and meta-analysis of the literature. We comprehensively searched the databases of MEDLINE and EMBASE from inception to October 2019. Included studies were prospective or retrospective cohort studies that reported the event rate of infective endocarditis in patients who underwent TAVR. Data from each study were combined using the random-effects method to calculate pooled incidence with 95% confidence intervals (CIs). A total of 30 studies consisting of 73 780 patients undergoing TAVR were included in this meta-analysis. Overall, the pooled estimated incidence of infective endocarditis following TAVR was 7 in 1000 patients (95% CI: 0.5-1%). For early infective endocarditis, the pooled estimated incidence was 8 per 1000 patients (95% CI: 0.5-1.1%). For late infective endocarditis, the pooled estimated incidence was 2 in 1000 patients (95% CI: 0.1-0.4%). Significantly,...Continue Reading

References

Jan 1, 1988·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·A Arvay, M Lengyel
Jul 1, 1985·Circulation·S B CalderwoodM J Buckley
Nov 1, 1984·Kokyu to junkan. Respiration & circulation·T NireiK Hirosawa
Feb 1, 1984·Circulation·T S IvertL A Bergdahl
Apr 4, 1994·The Medical Journal of Australia·R W Baird
Sep 29, 2001·Journal of Clinical Epidemiology·J A Sterne, M Egger
Apr 16, 2003·Heart·Rob Moss, Brad Munt
Sep 3, 2003·Journal of Cardiovascular Electrophysiology·J Thomas Bigger
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Oct 7, 2005·Journal of Clinical Microbiology·D RaoultG Habib
Jun 5, 2007·The Journal of the American Dental Association·UNKNOWN American Heart Association, UNKNOWN American Dental Association Division of Communications
Apr 22, 2008·International Journal of Epidemiology·Nikolaos A PatsopoulosJohn P A Ioannidis
Oct 29, 2008·Archives of Internal Medicine·Emanuele Durante-MangoniUNKNOWN International Collaboration on Endocarditis Prospective Cohort Study Group
Jul 22, 2009·PLoS Medicine·David MoherUNKNOWN PRISMA Group
Aug 12, 2009·Infectious Disease Clinics of North America·Jay R McDonald
Oct 20, 2011·BMJ : British Medical Journal·Julian P T HigginsUNKNOWN Cochrane Statistical Methods Group
Mar 27, 2012·The New England Journal of Medicine·Raj R MakkarUNKNOWN PARTNER Trial Investigators
Sep 28, 2012·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Miriam PulsWolfgang Schillinger
Apr 12, 2013·The New England Journal of Medicine·Bruno Hoen, Xavier Duval
Jul 17, 2013·JAMA Internal Medicine·Tahaniyat LalaniUNKNOWN International Collaboration on Endocarditis–Prospective Cohort Study Investigators
Sep 12, 2013·The Annals of Thoracic Surgery·David HolzheyVolkmar Falk
Apr 3, 2014·JAMA : the Journal of the American Medical Association·Jeffrey L Carson
Jul 7, 2014·The American Journal of Cardiology·Michael GotzmannAydan Ewers
Sep 10, 2014·Expert Review of Anti-infective Therapy·William R MillerCesar A Arias
Feb 24, 2015·JACC. Cardiovascular Interventions·Ignacio J Amat-SantosJosep Rodés-Cabau
Sep 8, 2015·Contemporary Clinical Trials·Rebecca DerSimonian, Nan Laird
Sep 17, 2015·Circulation·Larry M BaddourUNKNOWN American Heart Association Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular
Apr 7, 2016·Journal of the American College of Cardiology·G Michael DeebUNKNOWN CoreValve US Clinical Investigators
Jul 23, 2016·Hellenic Journal of Cardiology : HJC = Hellēnikē Kardiologikē Epitheōrēsē·Cenk SarıEngin Bozkurt
Sep 14, 2016·JAMA : the Journal of the American Medical Association·Ander RegueiroJosep Rodés-Cabau
Feb 9, 2017·The Annals of Thoracic Surgery·Christos G MihosOrlando Santana

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Citations

Oct 20, 2020·Expert Review of Cardiovascular Therapy·Christopher J AllenSimon R Redwood

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