Epidemiology of invasive fungal diseases among patients with haematological disorders in the Asia-Pacific: a prospective observational study

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
L Y HsuT Y Tan

Abstract

We conducted a 2-year multicentre prospective observational study to determine the epidemiology of and mortality associated with invasive fungal diseases (IFDs) among patients with haematological disorders in Asia. Eleven institutions from 8 countries/regions participated, with 412 subjects (28.2% possible, 38.3% probable and 33.5% proven IFDs) recruited. The epidemiology of IFDs in participating institutions was similar to Western centres, with Aspergillus spp. (65.9%) or Candida spp. (26.7%) causing the majority of probable and proven IFDs. The overall 30-day mortality was 22.1%. Progressive haematological disorder (odds ratio [OR] 5.192), invasive candidiasis (OR 3.679), and chronic renal disease (OR 6.677) were independently associated with mortality.

References

Jan 1, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D NeofytosK Marr
Jul 28, 2010·Bone Marrow Transplantation·J MaertensUNKNOWN Third European Conference on Infections in Leukemia
Jan 5, 2011·The Journal of Antimicrobial Chemotherapy·Livio PaganoNicole Blijlevens
Jan 6, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Alison G Freifeld Infectious Diseases Society of Americaa
Jun 15, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·O LortholaryUNKNOWN French Mycosis Study Group
Sep 13, 2011·Medical Mycology·Monica A Slavin, Arunaloke Chakrabarti

❮ Previous
Next ❯

Citations

Nov 5, 2016·Diagnostic Microbiology and Infectious Disease·Zi-Li ZhouUNKNOWN TSARY Hospitals
Dec 21, 2017·Intractable & Rare Diseases Research·Ghazal TansirUpendra Baitha
Mar 24, 2016·Virulence·Giulia Gustinetti, Malgorzata Mikulska
Jun 6, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Variya NganthaveePloyploen Phikulsod
Mar 12, 2020·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Biju GeorgeVikram Mathews
Jun 15, 2019·Laboratory Medicine·Nada N NawarMohamed A Emara
Mar 23, 2018·Journal of Fungi·Rukumani Devi VelayuthanDavid W Denning
Jul 3, 2017·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Jae-Ki ChoiDong-Gun Lee

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aspergillosis

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Aspergillosis (ASM)

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.