Epidemiology of invasive pneumococcal infection in children aged five years and under in Saudi Arabia: a five-year retrospective surveillance study

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Ziad A MemishAbdulhakeem O Thaqafi

Abstract

The epidemiology of invasive pneumococcal disease (IPD) in children aged <or=5 years in Saudi Arabia has not been described. We conducted a retrospective surveillance study to describe the epidemiology of IPD in the population of children aged <or=5 years served by the National Guard Health Affairs hospitals in central and western regions of Saudi Arabia. We reviewed the medical records of children <or=5 years old admitted to the King Abdulaziz Medical City hospitals in Riyadh and Jeddah with pneumococcal infections for the period January 1999 through December 2003. Only microbiologically confirmed IPD cases (meningitis or bacteremia) were included in the analysis. A total of 82 IPD cases, 19 (23.2%) meningitis and 63 (76.8%) bacteremia, were diagnosed during the five-year period. Of these, 12.2% (10/82) died, with a case-fatality slightly but insignificantly higher in cases of meningitis (15.8%) than bacteremia (11.1%). The average annual IPD incidence was 17.4 per 100,000 (4.0 for meningitis and 13.4 for bacteremia). The incidence was roughly similar in males and females (18.3 and 16.6, respectively; p=0.663) and was almost 4-fold higher in the first year of life compared to the next four years (40.6 and 11.5, respectively; p...Continue Reading

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Citations

Sep 15, 2015·Journal of Epidemiology and Global Health·Yagob AlmazrouWilliam P Hausdorff
Jun 19, 2014·Acta Microbiologica Et Immunologica Hungarica·Lakshmana Gowda KrishnappaPradeep Chikkabidare Shashidhar
Mar 24, 2018·World Journal of Pediatrics : WJP·Luisa SantangeloMario Giordano
Jul 15, 2015·The Journal of the Egyptian Public Health Association·Iman H DrazBassant S Meligy

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