PMID: 8605908Oct 1, 1995Paper

Epidemiology of penicillin-resistant Neisseria gonorrhoeae in Frankfurt, Germany

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
V SchäferV Brade

Abstract

In the present study 150 Neisseria gonorrhoeae strains from prostitutes in Frankfurt, Germany, were investigated for their in vitro susceptibility to eight antimicrobial agents by the agar dilution test. While 21.3% of gonococci were highly resistant to penicillin (MICs > or = 2 mg/l), 49.4% of the organisms were moderately sensitive (MICs = 0.125-0.5 mg/l) and only 29.3% of strains were fully susceptible to penicillin (MICs < or = 0.06 mg/l). No resistance to other antibiotics tested was observed, with the exception of doxycycline, to which overall resistance was 9.7%. Genotypic analysis of Neisseria gonorrhoeae by the restriction enzyme technique showed that most penicillin-resistant strains could be grouped into two main bacterial clones, whereas penicillin-susceptible isolates displayed a remarkable heterogeneity. This observation suggests that a restricted number of resistant Neisseria gonorrhoeae strains are likely to spread within the prostitute population of Frankfurt, Germany.

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Citations

May 31, 2006·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M EndersT Regnath
Dec 22, 1999·Microbes and Infection·Y T van Duynhoven
Jan 26, 1999·Sexually Transmitted Diseases·K P KyriakisE Frangouli
Jun 27, 2015·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·Anna LoenenbachV Bremer
May 8, 2014·International Journal of Medical Microbiology : IJMM·Nicole Nari HornUNKNOWN Working Party Antimicrobial Resistance of the Paul Ehrlich Society for Chemotherapy
Dec 1, 2012·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Susanne AbrahamPetra Spornraft-Ragaller
Nov 13, 1998·Journal of Applied Microbiology·C H MartinsD P Falcão
Jun 12, 1999·Journal of Clinical Microbiology·M Van LooverenH Goossens

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