PMID: 7009816Mar 1, 1981Paper

Epidemiology of pertussis, Atlanta, 1977

The Journal of Pediatrics
C V BroomeD W Fraser

Abstract

In the period April to October, 1977, an epidemic of pertussis in the outpatient population of a large metropolitan hospital involved 115 cases that were diagnosed by culture or direct fluorescent antibody tests. A study of secondary cases in household contacts showed attack rates of 81% in children under one year of age; attack rates decreased with increasing age to 8% in persons over 20 years of age. Vaccine efficacy was estimated to be 63%. There was no evidence of decreased efficacy with increasing time after vaccination. Fourteen asymptomatic FA-positive individuals were identified; four of these were also culture positive. Four were adults and ten were children. Nine of the ten children had received three or more vaccinations, compared to only 29 of 78 symptomatic children (P = 0.002).

References

Oct 25, 1979·The New England Journal of Medicine·J P KoplanD W Fraser
Sep 20, 1975·Lancet·C C LinnemannG S Englender
Aug 1, 1977·Journal of Clinical Microbiology·L H Field, C D Parker
Sep 23, 1978·British Medical Journal·D Jenkinson
Jun 16, 1979·British Medical Journal·R K Ditchburn
Nov 1, 1975·Medicine·L C Olson
Feb 1, 1976·American Journal of Epidemiology·O Miettinen
Nov 1, 1968·American Journal of Epidemiology·C C LinnemannM H Smith
Sep 1, 1951·The American Journal of the Medical Sciences·J E GORDON, R I HOOD

❮ Previous
Next ❯

Citations

Jun 1, 1988·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M BlennowM Granström
Oct 6, 1997·Mathematical Biosciences·H W Hethcote
Jan 28, 1984·Lancet
Jan 10, 1987·Lancet·J W Bass
Feb 1, 1984·The Journal of Hygiene·P E Fine, J A Clarkson
Oct 20, 1983·The New England Journal of Medicine·E W BrinkA R Hinman
Jan 1, 1988·Archives of Disease in Childhood·A Nicoll, A Gardner
Oct 24, 2007·Emerging Themes in Epidemiology·Aaron M WendelboeAnnelies Van Rie
Oct 31, 2006·Medicinski pregled·Vladimir PetrovićSlavica Stefanović
Sep 17, 2008·Journal of Continuing Education in Nursing·Ellyn MatthewsTammy Spencer
Mar 1, 1986·Current Problems in Pediatrics·F J CrossonA S Yeager
Sep 1, 1983·The Journal of Pediatrics·J MertsolaM K Viljanen
Jun 1, 1989·The Journal of Pediatrics·M C FisherD G Smith
Aug 1, 1985·The Journal of Pediatrics·T AoyamaT Iwata
Apr 1, 1997·The Journal of Pediatrics·B TrollforsJ B Robbins
Apr 7, 2007·The Pediatric Infectious Disease Journal·Aaron M WendelboeUNKNOWN Infant Pertussis Study Group
May 12, 1998·The Pediatric Infectious Disease Journal·K L MoshalK L McGowan
Apr 1, 1997·The Pediatric Infectious Disease Journal·S Black
Oct 1, 1987·Tropical Doctor·A S MullerD S Pratt
May 18, 1987·The Medical Journal of Australia·D J Hansman
Nov 1, 1984·Journal of Clinical Microbiology·P H Gilligan, M C Fisher

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.