Epidemiology of soy exposures and breast cancer risk

British Journal of Cancer
A H WuM C Pike

Abstract

Most of the early studies published on soy and breast cancer were not designed to test the effect of soy; the assessment of soy intake was usually crude and few potential confounders were considered in the analysis. In this review, we focused on studies with relatively complete assessment of dietary soy exposure in the targeted populations and appropriate consideration for potential confounders in the statistical analysis of study data. Meta-analysis of the 8 (1 cohort, 7 case-control) studies conducted in high-soy-consuming Asians show a significant trend of decreasing risk with increasing soy food intake. Compared to the lowest level of soy food intake (<or=5 mg isoflavones per day), risk was intermediate (OR=0.88, 95% confidence interval (CI)=0.78-0.98) among those with modest ( approximately 10 mg isoflavones per day) intake and lowest (OR=0.71, 95% CI=0.60-0.85) among those with high intake (>or=20 mg isoflavones per day). In contrast, soy intake was unrelated to breast cancer risk in studies conducted in the 11 low-soy-consuming Western populations whose average highest and lowest soy isoflavone intake levels were around 0.8 and 0.15 mg per day, respectively. Thus, the evidence to date, based largely on case-control studi...Continue Reading

References

May 18, 1991·Lancet·H P LeeN E Day
Jun 1, 1995·British Journal of Cancer·J M YuanM C Yu
Feb 1, 1997·Breast Cancer Research and Treatment·J S WitteR W Haile
Sep 5, 2001·American Journal of Epidemiology·P L Horn-RossE J Perez-Stable
Jul 31, 2002·Cancer Causes & Control : CCC·Pamela L Horn-RossAl Ziogas
Aug 22, 2002·Carcinogenesis·Anna H WuMalcolm C Pike
Dec 7, 2002·The Journal of Nutrition·Kenneth D R SetchellEva Lydeking-Olsen
Jun 19, 2003·Journal of the National Cancer Institute·Seiichiro YamamotoUNKNOWN Japan Public Health Center-Based Prospective Study on Cancer Cardiovascular Diseases Group
Sep 2, 2003·International Journal of Cancer. Journal International Du Cancer·Kaoru HiroseKazuo Tajima
Oct 2, 2003·British Journal of Cancer·J PetersonD Trichopoulos
Jan 30, 2004·The American Journal of Clinical Nutrition·Lital Keinan-BokerPetra H M Peeters
Apr 8, 2004·International Journal of Cancer. Journal International Du Cancer·Jakob LinseisenUNKNOWN German Case-Control Study
Apr 13, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Cristina BosettiCarlo La Vecchia
May 11, 2005·The American Journal of Clinical Nutrition·Anna H WuMalcolm C Pike
Jun 9, 2005·British Journal of Cancer·K HiroseK Tajima
Jun 28, 2005·Breast Cancer Research and Treatment·Sonia M BoyapatiWei Zheng
Sep 1, 2005·Cancer Causes & Control : CCC·Marion M LeeAndrew Huang
Apr 6, 2006·Journal of the National Cancer Institute·Bruce J TrockRobert Clarke
Sep 21, 2006·Journal of the National Cancer Institute·Mark MessinaJohanna W Lampe
Nov 18, 2006·Cancer Causes & Control : CCC·Joanne ThanosLilian U Thompson
Nov 30, 2006·International Journal of Cancer. Journal International Du Cancer·Anna H WuMalcolm C Pike
Dec 13, 2006·American Journal of Epidemiology·Brian N FinkMarilie D Gammon
Dec 14, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Marina S TouillaudFrançoise Clavel-Chapelon
Jan 4, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Martijn VerheusPetra H M Peeters
May 31, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Anna H WuDaniel R Doerge

❮ Previous
Next ❯

Citations

Jan 24, 2014·Japanese Journal of Clinical Oncology·Chisato NagataUNKNOWN Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan
Nov 29, 2013·Toxicological Sciences : an Official Journal of the Society of Toxicology·Anne KatchyCecilia Williams
Feb 4, 2014·Journal of Neurosurgery·Joellen M SchildkrautElizabeth B Claus
May 14, 2014·Breast Cancer Research and Treatment·Graham A ColditzCatherine S Berkey
Sep 6, 2014·Journal of the National Cancer Institute·Moshe ShikeLarry Norton
Jun 5, 2008·Nutrition Journal·Mark J Messina, Charles E Wood
Dec 10, 2008·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Anna H WuMimi C Yu
Mar 27, 2009·The Journal of Nutrition·Gertraud MaskarinecWilliam W Wong
Apr 8, 2009·Journal of Inflammation·Gertraud MaskarinecRobert V Cooney
May 1, 2009·The American Journal of Clinical Nutrition·Sang-Ah LeeWei Zheng
Oct 1, 2009·Cancer Prevention Research·Marc T GoodmanLaurence N Kolonel
Oct 1, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Barbara J FuhrmanRegina G Ziegler
Oct 20, 2009·Nutrition and Cancer·Gertraud MaskarinecJ Mark Cline
Dec 10, 2009·JAMA : the Journal of the American Medical Association·Xiao Ou ShuWei Lu
Feb 26, 2010·The American Journal of Clinical Nutrition·Lesley M ButlerMimi C Yu
May 12, 2010·Omics : a Journal of Integrative Biology·Samir SatihDominique J Bernard-Gallon
May 21, 2010·The Journal of Nutrition·S Coosje DijkstraDavid B Thomas
Oct 29, 2010·The Journal of Nutrition·Leena Hilakivi-ClarkeWilliam Helferich
Dec 24, 2010·The American Journal of Clinical Nutrition·Francene M SteinbergWilliam W Wong
Oct 1, 2011·The American Journal of Clinical Nutrition·Kenneth D R SetchellMark J Messina
Oct 12, 2011·Food & Function·Yukiko MorimotoGertraud Maskarinec
Feb 4, 2012·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Eunjung LeeAnna H Wu
Feb 15, 2012·Food & Function·Cherisse SenGertraud Maskarinec
Jun 21, 2012·European Journal of Clinical Nutrition·G MaskarinecA A Franke
Feb 19, 2013·Journal of Mammary Gland Biology and Neoplasia·Madisa B Macon, Suzanne E Fenton
Dec 7, 2013·PloS One·Heidi FritzDean Fergusson
Mar 24, 2011·American Journal of Epidemiology·Keiko WadaChisato Nagata
Aug 10, 2012·The British Journal of Nutrition·Mark MessinaDavid J A Jenkins
Nov 30, 2011·Public Health Nutrition·Urmila ChandranElisa V Bandera
Aug 3, 2012·Nutrition Research Reviews·Dorothy TeegardenSophie A Lelièvre
Nov 20, 2012·The Journal of Endocrinology·H El Sheikh SaadM Perrot-Applanat
May 7, 2013·The Journal of Endocrinology·Maria Theresa E MontalesRosalia C M Simmen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Norie KurahashiJapan Public Health Center-Based Prospective Study Group
© 2021 Meta ULC. All rights reserved