Epidemiology of viral infections and evaluation of the potential benefit of OM-85 BV on the virologic status of children attending day-care centers

Respiration; International Review of Thoracic Diseases
M AymardJ Gillet

Abstract

Viral investigations were performed during 4 winter seasons (88/89, 89/90, 92/93, 93/94) in children attending day-care centers (DCCs) in the Rhône Département in eastern France. Over the total observation period of 4 winter seasons, 780 children were screened with a nasal swab for the presence of viruses. Of those, 230 (29.5%) had a positive viral culture. The viruses identified were respiratory syncytial virus (RSV), influenza A and B virus, parainfluenza virus, coronavirus, rhinovirus, adenovirus and enterovirus. During that time, 83 epidemic events in 47 DCC were recorded. A particular virus was judged to be causally related to an epidemic if the identical virus was isolated in > or = 3 children during the same outbreak of respiratory diseases. Thus, in 51 cases (61.4%) of all epidemics, the following viruses were responsible for an epidemic: RSV (n = 23), coronavirus (n = 10) (only during the season of 1993-1994), influenza A virus (n = 6), rhinovirus (n = 4), enterovirus (n = 4), adenovirus (n = 3) and parainfluenza virus (n = 1). Except for the somewhat surprising accumulation of coronavirus epidemics during the winter of 1993-1994, there were only minor seasonal variations from one year to another. As expected, RSV acco...Continue Reading

Citations

Oct 12, 2000·The Journal of Infection·M R KimG M Lee
Apr 3, 2003·The Pediatric Infectious Disease Journal·Lone Graff StensballeEric A Simoes
Feb 5, 2003·Pediatric Pulmonology·Leda Solano de Freitas SouzaEurico Arruda
Oct 21, 2006·The Cochrane Database of Systematic Reviews·B E Del-Rio-NavarroJ J L Sienra-Monge

Related Concepts

OM-85 BV
Immunologic Adjuvants
Cell Extracts
Day Care Centers for Children
Disease Outbreaks
Seasonal Variation
Virus Diseases
Zoophaginae

Related Feeds

Acute viral rhinopharyngitis

Acute viral rhinopharyngitis, also known as "common cold", is an acute, self-limiting viral infection of the upper respiratory tract involving the nose, sinuses, pharynx and larynx. Discover the latest research on acute viral rhinopharyngitis here.