Epidermal interleukin 1 in normal skin of patients with HIV infection

The British Journal of Dermatology
B DrénoP Litoux

Abstract

Interleukin 1 (IL-1) in the epidermis plays an important role together with Langerhans cells in the activation of the T cells. To determine whether IL-1 could be located in the normal epidermis of 54 patients with HIV infection and related to the stage of the disease, an indirect immunofluorescence technique was used. Intense epidermal fluorescence to IL-1 was noted in the asymptomatic stage II of the disease, whereas there was minimal reactivity in the other stages.

References

Apr 1, 1988·The British Journal of Dermatology·B DrénoP Litoux
Feb 1, 1987·The Journal of Investigative Dermatology·E TschachlerG Stingl
Mar 1, 1988·The Journal of Investigative Dermatology·V A TronD N Sauder
Jun 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·M P BevilacquaM A Gimbrone
Nov 29, 1984·The New England Journal of Medicine·C A Dinarello
May 17, 1984·The New England Journal of Medicine·D V BelsitoG J Thorbecke

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Citations

Aug 1, 1994·Clinical and Experimental Immunology·A CarrD A Cooper
Jan 7, 1998·Immunological Reviews·O J CohenA S Fauci

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