EPIDERMOID CARCINOMA IN THE NEOVAGINA OF A PATIENT WITH MAYER-ROKITANSKY-KÜSTER-HAUSER SYNDROME. CASE REPORT AND LITERATURE REVIEW

Revista colombiana de obstetricia y ginecología
Marta Fernández-RuizMaría Del Valle Aguilar-Martín

Abstract

To present the case of a squamous carcinoma in the neovagina of a patient with Mayer-Rokitansky-Küster-Hauser syndrome and review of the literature related to treatment and prognosis of vaginal neoplasms or HPV infection in transgender women or with MRKH syndrome. A 56-year-old woman consulted to the Hospital Universitario of Sevilla (Spain). During the clinical examination, a exophytic tumor at the bottom of the vagina was found and the biopsy reported squamous carcinoma and positive nucleic acid amplification test for human papilloma (HPV) type 16. A literature search of case reports, case series and observational studies published from 2000 to October 2019 in English and Spanish was performed in Medline via PubMed, with the follow- ing terms: "congenital abnormalities"; "Mullerian aplasia"; "neovagina"; "Vaginal neoplasms"; "Squamous carcinoma"; "HPV infection" was performed. 14 studies were finally included; seven corresponded to squamous cell carcinoma, three to adenocarcinoma and four reported HPV infection only. All of the squamous cell carcinomas were at advanced stages due to local or lymphatic compro- mise and received radiotherapy with concomitant chemotherapy or radical surgery. The prognosis was bad in three of the...Continue Reading

References

Dec 26, 2001·Gynecologic Oncology·Eric SteinerPaul Georg Knapstein
Apr 26, 2002·Gynecologic Oncology·Devansu S TewariRobert A Burger
Apr 16, 2005·The Lancet Oncology·Vincent CoglianoUNKNOWN WHO International Agency for Research on Cancer
Sep 27, 2006·Zentralblatt für Gynäkologie·C LiebrichK U Petry
Nov 13, 2007·BJOG : an International Journal of Obstetrics and Gynaecology·L MichalaS M Creighton
Jul 30, 2011·Indian Journal of Sexually Transmitted Diseases and AIDS·Rahul DixitY S Marfatia
Aug 22, 2012·Reproductive Biology and Endocrinology : RB&E·Patricia G OppeltAndreas Mueller
Sep 3, 2013·Journal of Lower Genital Tract Disease·Hugo M FernandesTom W Jobling
Jun 19, 2014·The Journal of Family Planning and Reproductive Health Care·Mary HernonS M Creighton
Jul 15, 2015·World Journal of Surgical Oncology·Yoshiaki KitaShoji Natsugoe
Jul 16, 2016·Sexually Transmitted Diseases·Wouter B van der SluisMargriet G Mullender
Oct 8, 2016·Clinical Genetics·L FontanaM Miozzo
Aug 31, 2017·International Journal of STD & AIDS·Jesús BolloEduard M Targarona
Apr 29, 2018·World Journal of Surgical Oncology·Kazunosuke YamadaYukihide Kanemitsu

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.